Almășan Oana, Duncea Ioana, Kui Andreea, Buduru Smaranda
Prosthetic Dentistry and Dental Materials Department, Iuliu Hatieganu University of Medicine and Pharmacy, 32 Clinicilor Street, 400006 Cluj-Napoca, Romania.
Healthcare (Basel). 2022 Mar 26;10(4):624. doi: 10.3390/healthcare10040624.
As the human papillomavirus (HPV) infections are detected in healthy oral mucosa as well as in oral lesions, dental practitioners have an important role in detecting any possible lesions that might be caused by this virus. Therefore, the aim of this study was to investigate the outcomes of orthodontic treatments and HPV infections and to report a rare case of ongoing orthodontic treatment superposed on an HPV infection.
An electronic English literature research of the articles published between the years 2011-2021 was conducted between December 2021-February 2022, accessing PubMed, Web of Science, Embase, Scopus, and Google Scholar. The terms "HPV", "orthodontics", "orthodontic treatment", "tooth movement", "tooth mobility", and "malocclusion" were searched. The following inclusion criteria were pursued: articles published in English language; studies reporting HPV infection in subjects with past or ongoing orthodontic treatment; and case reports of subjects with HPV and orthodontic treatment. Exclusion criteria were: articles in languages other than English, studies related to malignancies other than HPV and orthodontic treatment; and studies reporting patients with HPV and no orthodontic treatment.
Following the systematic review, which includes six papers, a case of orthodontic treatment superposed on a HPV infection is presented.
Incumbent, postponed HPV infection on an ongoing orthodontic treatment might affect treatment outcome and patient compliance.
由于在健康的口腔黏膜以及口腔病变中均检测到人类乳头瘤病毒（HPV）感染，牙科从业者在检测由该病毒可能引起的任何潜在病变方面发挥着重要作用。因此，本研究的目的是调查正畸治疗与HPV感染的结果，并报告1例罕见的正在进行正畸治疗且合并HPV感染的病例。
于2021年12月至2022年2月期间，通过检索PubMed、科学网、Embase、Scopus和谷歌学术，对2011年至2021年间发表的英文文献进行电子检索。检索词包括“HPV”“正畸学”“正畸治疗”“牙齿移动”“牙齿松动度”和“错牙合畸形”。采用以下纳入标准：以英文发表的文章；报告过去或正在进行正畸治疗的受试者中HPV感染情况的研究；以及HPV与正畸治疗相关的病例报告。排除标准为：非英文文章；与HPV和正畸治疗以外的恶性肿瘤相关的研究；以及报告有HPV感染但未接受正畸治疗的患者的研究。
在纳入6篇论文的系统评价之后，呈现了1例正畸治疗合并HPV感染的病例。
在正在进行的正畸治疗中发生或延迟的HPV感染可能会影响治疗结果和患者的依从性。
