Kasten Mary J
Division of Public Health, Infectious Diseases and Occupational Medicine, Mayo Clinic, Rochester, MN 55901, USA.
Pathogens. 2022 Mar 22;11(4):380. doi: 10.3390/pathogens11040380.
Life-changing progress has been made over the past 30 years in the treatment of HIV infection. HIV has transformed from an illness that resulted in one complication after another and nearly always resulted in death to a chronic illness that for most patients is more easily managed than diabetes or heart disease. Antiretroviral therapy (ART) is now simple and well-tolerated. The most important priority of HIV treatment is ensuring that people living with HIV stay on continuous, effective ART. ART, although not curative, suppresses the virus and allows the immune system to recover. Even when the CD4 count remains low, suppressive ART helps prevent opportunistic infections and other HIV related complications. (1) Suppressive ART is important not only to the individual living with HIV health but is an important public health goal since people living with HIV will not transmit HIV to their sexual partners if their viral load is undetectable. (2) A respectful, culturally appropriate patient-provider relationship is one of the most important factors in keeping people living with HIV engaged in care. (3) Persons living with HIV deserve both excellent HIV and primary care. Some communities have providers that are experts in both, but often people living with HIV receive the best care by collaboration between their primary care provider and an HIV expert. This article is written to help primary care givers who are not HIV experts provide appropriate primary care to their patients who are living with HIV and emphasizes issues that deserve additional attention in people living with HIV compared to the general population.
在过去30年里,HIV感染的治疗取得了改变生活的进展。HIV已从一种引发一连串并发症且几乎总会导致死亡的疾病转变为一种慢性病,对大多数患者来说,它比糖尿病或心脏病更容易控制。抗逆转录病毒疗法(ART)现在操作简单且耐受性良好。HIV治疗的首要重点是确保HIV感染者持续接受有效的ART治疗。ART虽不能治愈,但能抑制病毒并使免疫系统恢复。即使CD4细胞计数仍很低,抑制性ART也有助于预防机会性感染和其他与HIV相关的并发症。(1)抑制性ART不仅对HIV感染者的健康很重要,也是一项重要的公共卫生目标,因为如果HIV感染者的病毒载量检测不到,他们就不会将HIV传播给性伴侣。(2)尊重患者、符合文化背景的医患关系是使HIV感染者坚持接受治疗的最重要因素之一。(3)HIV感染者既需要优质的HIV专科护理,也需要初级保健。一些社区有同时擅长这两方面的医疗服务提供者,但HIV感染者通常通过其初级保健提供者与HIV专家合作才能获得最佳护理。撰写本文旨在帮助并非HIV专家的初级保健人员为其HIV感染患者提供适当的初级保健,并强调与普通人群相比,HIV感染者中值得额外关注的问题。