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焊工炭疽:一种职业病综述

Welder's Anthrax: A Review of an Occupational Disease.

作者信息

de Perio Marie A, Hendricks Katherine A, Dowell Chad H, Bower William A, Burton Nancy C, Dawson Patrick, Schrodt Caroline A, Salzer Johanna S, Marston Chung K, Feldmann Karl, Hoffmaster Alex R, Antonini James M

机构信息

Office of the Director, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Cincinnati, OH 45226, USA.

Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.

出版信息

Pathogens. 2022 Mar 26;11(4):402. doi: 10.3390/pathogens11040402.

Abstract

Since 1997, nine cases of severe pneumonia, caused by species within the group and with a presentation similar to that of inhalation anthrax, were reported in seemingly immunocompetent metalworkers, with most being welders. In seven of the cases, isolates were found to harbor a plasmid similar to the pXO1 that encodes anthrax toxins. In this paper, we review the literature on the group spp. pneumonia among welders and other metalworkers, which we term welder's anthrax. We describe the epidemiology, including more information on two cases of welder's anthrax in 2020. We also describe the health risks associated with welding, potential mechanisms of infection and pathological damage, prevention measures according to the hierarchy of controls, and clinical and public health considerations. Considering occupational risk factors and controlling exposure to welding fumes and gases among workers, according to the hierarchy of controls, should help prevent disease transmission in the workplace.

摘要

自1997年以来,在看似免疫功能正常的金属工人(大多数是焊工)中报告了9例由该菌群内的物种引起的严重肺炎病例,其临床表现与吸入性炭疽相似。在其中7例病例中,分离出的菌株携带一种与编码炭疽毒素的pXO1质粒相似的质粒。在本文中,我们回顾了关于焊工和其他金属工人中该菌群物种肺炎的文献,我们将其称为焊工炭疽。我们描述了其流行病学,包括2020年两例焊工炭疽的更多信息。我们还描述了与焊接相关的健康风险、潜在的感染机制和病理损害、根据控制层级采取的预防措施以及临床和公共卫生方面的考虑。根据控制层级,考虑职业风险因素并控制工人接触焊接烟尘和气体,应有助于预防工作场所的疾病传播。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d76/9029013/95fd0b770faa/pathogens-11-00402-g001.jpg

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