Mandurino-Mirizzi Alessandro, Munafò Andrea, Crimi Gabriele
Division of Cardiology, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy.
Interventional Cardiology Unit, Cardio-Thoraco Vascular Department (DICATOV), IRCCS Ospedale Policlinico San Martino, 16100 Genova, Italy.
J Clin Med. 2022 Apr 13;11(8):2167. doi: 10.3390/jcm11082167.
Contrast-associated acute kidney injury (CA-AKI) is an impairment of renal function, which occurs within days of intravascular administration of iodinated contrast media. Taking into account that minimally invasive cardiac interventions are becoming increasingly popular, compared to traditional surgery, given their impact on prognosis and costs, CA-AKI remains a subject of increasing interest for patients and physicians. This review summarizes the epidemiology and risk stratification, diagnostic criteria, pathophysiology and clinical implications of CA-AKI, providing evidence for the most studied preventive strategies.
对比剂相关急性肾损伤(CA-AKI)是一种肾功能损害,发生在血管内注射碘化造影剂后的数天内。鉴于与传统手术相比,微创心脏介入治疗因其对预后和成本的影响而越来越受欢迎,CA-AKI仍然是患者和医生日益关注的一个问题。这篇综述总结了CA-AKI的流行病学、风险分层、诊断标准、病理生理学和临床意义,为研究最多的预防策略提供了证据。