Institute of Anatomy, First Faculty of Medicine, Charles University, 128 00 Prague, Czech Republic.
Biotechnology and Biomedicine Center, Academy of Science and Charles University, 252 50 Vestec, Czech Republic.
Int J Mol Sci. 2022 Apr 7;23(8):4071. doi: 10.3390/ijms23084071.
Cancer represents an extremely complicated ecosystem where cancer cells communicate with non-cancer cells present in the tumour niche through intercellular contacts, paracrine production of bioactive factors and extracellular vesicles, such as exosomes [...].
癌症代表了一个极其复杂的生态系统,其中癌细胞通过细胞间接触、旁分泌生物活性因子和细胞外囊泡(如外泌体)与肿瘤微环境中的非癌细胞进行通讯。