Global Health and Tropical Medicine (GHTM), Institute of Hygiene and Tropical Medicine, Universidade Nova de Lisboa (IHMT-UNL), Rua da Junqueira 100, 1349-008 Lisbon, Portugal.
Ministry of Health, Av. Eduardo Mondlane 1008, Maputo 264, Mozambique.
Int J Environ Res Public Health. 2022 Apr 11;19(8):4568. doi: 10.3390/ijerph19084568.
There has been tremendous progress in the fight against HIV worldwide; however, challenges persist in the control of HIV infection. These challenges include the high prevalence of late presenters. There are many disadvantages of late presentation-from reduced survival of the infected person to the risk of transmitting the infection. This research aims to analyze the factors that influence the late presentation in patients attending Ndlavela Health Center in Mozambique.
A retrospective cross-sectional study was carried out at Ndlavela Health Center including patients diagnosed with HIV between 2015 and 2020. The European Late Presenter Consensus working group definitions were used, and univariate and multivariate logistic regression were used to identify factors associated with late presentation.
In total, 519 participants were included in the study, of which nearly 47% were classified as late presenters. The male gender (AOR = 2.41), clinical suspicious test (AOR = 4.03), initiated by the health professional (AOR = 2.1,9), and fear of stigma (AOR = 2.80) were the main risk factors for late HIV presentation.
Factors that are potentially determinant for late HIV presentation were identified. Actions are needed to focus on risk factors that are most likely to delay presentation.
在全球范围内,与艾滋病的斗争已经取得了巨大的进展;然而,在控制艾滋病毒感染方面仍然存在挑战。这些挑战包括大量晚期患者的出现。晚期出现有很多缺点——从感染者的生存机会减少到感染传播的风险。这项研究旨在分析影响莫桑比克恩德拉韦拉医疗中心就诊患者出现晚期症状的因素。
在恩德拉韦拉医疗中心进行了一项回顾性的横断面研究,该研究纳入了 2015 年至 2020 年间被诊断为 HIV 阳性的患者。使用了欧洲晚期患者共识工作组的定义,并进行了单变量和多变量逻辑回归分析,以确定与晚期出现相关的因素。
共有 519 名参与者纳入研究,其中近 47%的患者被归类为晚期出现者。男性(AOR = 2.41)、临床可疑检测(AOR = 4.03)、由卫生专业人员启动(AOR = 2.1,9)和对耻辱感的恐惧(AOR = 2.80)是晚期 HIV 出现的主要危险因素。
确定了与晚期 HIV 出现相关的潜在决定因素。需要采取行动,重点关注最有可能导致出现延迟的危险因素。