[秘鲁一家社会保障医院成年患者的HIV晚期诊断与疾病进展]
[Late diagnosis and advanced disease of HIV in adult patients from a Peruvian social security hospital].
作者信息
Maquera-Afaray Julio, Cvetkovic-Vega Aleksandar, Cárdenas Matlin M, Kälviäinen Helga, Mejia Christian R
机构信息
Universidad Peruana Cayetano Heredia, Lima, Perú.
Hospital Nacional Guillermo Almenara Irigoyen, Lima, Perú.
出版信息
Rev Chilena Infectol. 2016 Oct;33(Suppl 1):20-26. doi: 10.4067/S0716-10182016000700003.
BACKGROUND
The delayed HIV diagnosis with CD4 count is a public health problem.
OBJECTIVE
To determinate the frequency and the factors associated with a late diagnosis (LD) and to an advanced disease (AD) of HIV infection in patients from a Peruvian hospital.
MATERIALS AND METHODS
Analytic and transversal study of secondary data from adult's patients diagnostic with HIV during the period 1999-2012.
RESULTS AND CONCLUSIONS
From 1,714 patients, 82.6% (1416) had LD, and 64.5% (1106) were diagnostic with AD. Were associated with them: being of male sex (LD: 17% and AD: 28%; p < 0.001), have between 41-60 years (LD: 9% and AD: 15%; p < 0.001), have more than 60 years old (LD: 14% and AD: 23%; p < 0.003), being bisexual (LD: 18% and AD: 43%; p < 0.001), drugs abusers (LD: 24% and AD: 64%; p < 0.001). Being heterosexual was associated with less frequency (LD: 12% and AD: 19%; p < 0.001). The frequency of LD and AD of HIV are high and factors associated with them were male sex, being 40 years old or more, and belonging to sexually risk groups (homosexuals and bisexuals) and drugs abusers.
背景
通过CD4计数延迟诊断HIV是一个公共卫生问题。
目的
确定秘鲁一家医院中HIV感染患者的晚期诊断（LD）和疾病进展（AD）的频率及相关因素。
材料与方法
对1999年至2012年期间确诊为HIV的成年患者的二手数据进行分析性横断面研究。
结果与结论
在1714例患者中，82.6%（1416例）有晚期诊断，64.5%（1106例）被诊断为疾病进展。与之相关的因素有：男性（晚期诊断：17%，疾病进展：28%；p<0.001），年龄在41 - 60岁之间（晚期诊断：9%，疾病进展：15%；p<0.001），60岁以上（晚期诊断：14%，疾病进展：23%；p<0.003），双性恋者（晚期诊断：18%，疾病进展：43%；p<0.001），药物滥用者（晚期诊断：24%，疾病进展：64%；p<0.001）。异性恋者的频率较低（晚期诊断：12%，疾病进展：19%；p<0.001）。HIV的晚期诊断和疾病进展频率较高，与之相关的因素是男性、40岁及以上、属于性风险群体（同性恋者和双性恋者）以及药物滥用者。
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