Cardiology Unit, Fondazione Toscana Gabriele Monasterio, 54100 Massa, Italy.
Human Anatomy and Sport Medicine Division, Department of Public Health, University of Naples Federico II, 80131 Naples, Italy.
Int J Environ Res Public Health. 2022 Apr 15;19(8):4809. doi: 10.3390/ijerph19084809.
Penetrating aortic ulceration (PAU) is an acute aortic syndrome similar to aortic dissection and intramural hematoma. It is the result of a tunica intima ulceration due to atherosclerotic disease. This clinical condition can lead to serious complications and a poor short-term prognosis, especially in high-surgical-risk patients. We report three cases of patients referred to "Ospedale del Cuore" of Massa (Italy) with PAU at the aortic arch-proximal descending aorta level who could not undergo surgical intervention. For the first time in Italy, we successfully treated these patients with a full percutaneous implantation of a Castor branched aortic stent graft. Our case series shows that this type of endovascular graft is an effective, safe, and feasible treatment for PAU involving a distal aortic arch and avoiding surgery and related complications.
穿透性主动脉溃疡（PAU）是一种类似于主动脉夹层和壁内血肿的急性主动脉综合征。它是由于动脉粥样硬化疾病导致的内膜溃疡引起的。这种临床情况可能导致严重的并发症和不良的短期预后，尤其是在高手术风险的患者中。我们报告了意大利马萨的“Ospedale del Cuore”转诊的 3 例患者，他们患有主动脉弓-降主动脉近端的 PAU，无法进行手术干预。我们首次在意大利成功地使用全经皮植入 Castor 分支主动脉支架移植物治疗了这些患者。我们的病例系列表明，这种类型的血管内移植物对于涉及远端主动脉弓的 PAU 是一种有效、安全且可行的治疗方法，可以避免手术及相关并发症。
