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临床严重肥胖患者的心理干预和减肥手术——一项基于贝叶斯荟萃分析的系统评价。

Psychological Interventions and Bariatric Surgery among People with Clinically Severe Obesity-A Systematic Review with Bayesian Meta-Analysis.

机构信息

Chair of Epidemiology and Preventive Medicine, Department of Hygiene and Dietetics, Jagiellonian University Medical College, 31-034 Krakow, Poland.

Systematic Reviews Unit, Jagiellonian University Medical College, 31-034 Krakow, Poland.

出版信息

Nutrients. 2022 Apr 12;14(8):1592. doi: 10.3390/nu14081592.

Abstract

AIM

To assess the effectiveness of perioperative psychological interventions provided to patients with clinically severe obesity undergoing bariatric surgery regarding weight loss, BMI, quality of life, and psychosocial health using the Bayesian approach.

METHODS

We considered randomised trials that assessed the beneficial and harmful effects of perioperative psychological interventions in people with clinically severe obesity undergoing bariatric surgery. We searched four data sources from inception to 3 October 2021. The authors independently selected studies for inclusion, extracted data, and assessed the risk of bias. We conducted a meta-analysis using a Bayesian approach.

PROSPERO

CRD42017077724.

RESULTS

Of 13,355 identified records, we included nine studies (published in 27 papers with 1060 participants (365 males; 693 females, 2 people with missing data)). Perioperative psychological interventions may provide little or no benefit for BMI (the last reported follow-up: MD [95% credible intervals] = -0.58 [-1.32, 0.15]; BF = 0.65; 7 studies; very low certainty of evidence) and weight loss (the last reported follow-up: MD = -0.50 [-2.21, 0.77]; BF = 1.24, 9 studies, very low certainty of evidence). Regarding psychosocial outcomes, the direction of the effect was mainly inconsistent, and the certainty of the evidence was low to very low.

CONCLUSIONS

Evidence is anecdotal according to Bayesian factors and uncertain whether perioperative psychological interventions may affect weight-related and psychosocial outcomes in people with clinically severe obesity undergoing bariatric surgery. As the results are ambiguous, we suggest conducting more high-quality studies in the field to estimate the true effect, its direction, and improve confidence in the body of evidence.

摘要

目的

采用贝叶斯方法评估围手术期心理干预对接受减重手术的临床重度肥胖患者的减肥效果、体重指数、生活质量和心理社会健康的影响。

方法

我们考虑了评估围手术期心理干预对接受减重手术的临床重度肥胖患者的有益和有害影响的随机试验。我们从成立到 2021 年 10 月 3 日搜索了四个数据源。作者独立选择纳入的研究,提取数据,并评估偏倚风险。我们采用贝叶斯方法进行荟萃分析。

前瞻性

CRD42017077724。

结果

在 13355 条确定的记录中,我们纳入了 9 项研究(发表在 27 篇论文中,共 1060 名参与者(365 名男性;693 名女性,2 人数据缺失))。围手术期心理干预可能对 BMI(最后一次报告的随访:MD [95%可信区间] = -0.58 [-1.32, 0.15];BF = 0.65;7 项研究;极低确定性证据)和体重减轻(最后一次报告的随访:MD = -0.50 [-2.21, 0.77];BF = 1.24,9 项研究,极低确定性证据)几乎没有或没有益处。关于心理社会结果,效应的方向主要不一致,证据的确定性低至极低。

结论

根据贝叶斯因子,证据是轶事证据,不确定围手术期心理干预是否会影响接受减重手术的临床重度肥胖患者的体重相关和心理社会结果。由于结果不明确,我们建议在该领域开展更多高质量的研究,以估计真实效果、其方向,并提高对证据体的信心。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ccb/9024573/81fd9d63481f/nutrients-14-01592-g001.jpg

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