Department of Obstetrics and Gynecology, Semmelweis University, Üllői Street 78/a, 1082 Budapest, Hungary.
Workgroup of Research Management, Doctoral School, Semmelweis University, Üllői Street 22, 1085 Budapest, Hungary.
Nutrients. 2022 Apr 15;14(8):1649. doi: 10.3390/nu14081649.
Polycystic ovary syndrome (PCOS) is one of the most common endocrine reproductive disorders in women. Vitamin D deficiency is also quite common in this condition. The degree of vitamin D deficiency correlates with the severity of PCOS. Both male and female vitamin D levels play a role in fertility and affect the outcomes of in vitro fertilization (IVF). Moreover, fertility and IVF indicators are improved by vitamin D not only in healthy women but in those diagnosed with PCOS. Both vitamin D deficiency and PCOS increase pregnancy-related complications. Vitamin D supplementation and optimal vitamin D levels decrease both maternal and fetal risk for complications and adverse events. Furthermore, vitamin D supplementation may ameliorate or even prevent pregnancy-related reversible bone loss in mothers. This review emphasizes the roles of vitamin D deficiency and vitamin D supplementation and their correlation with PCOS regarding reproductive health.
多囊卵巢综合征（PCOS）是女性最常见的内分泌生殖系统疾病之一。这种情况下维生素 D 缺乏也很常见。维生素 D 缺乏的程度与 PCOS 的严重程度相关。男性和女性的维生素 D 水平都对生育能力起着作用，并影响体外受精（IVF）的结果。此外，维生素 D 不仅可以改善健康女性的生育和 IVF 指标，也可以改善 PCOS 患者的生育和 IVF 指标。维生素 D 缺乏和 PCOS 都会增加与妊娠相关的并发症。维生素 D 补充和最佳维生素 D 水平可以降低母婴并发症和不良事件的风险。此外，维生素 D 补充可能改善甚至预防与妊娠相关的母亲可逆性骨丢失。这篇综述强调了维生素 D 缺乏和维生素 D 补充及其与 PCOS 对生殖健康的相关性的作用。
