Department of Diagnostic Radiology, University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico.
Department of Pathology and Laboratory Medicine, University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico.
Am J Case Rep. 2022 Apr 23;23:e935115. doi: 10.12659/AJCR.935115.
BACKGROUND Dermoid cysts are rare benign intracranial tumors that usually present classic computed tomography (CT) and magnetic resonance imaging (MRI) characteristics, allowing for relatively simple diagnostic confirmation. Atypical imaging features can occur due to their diverse ectodermal-derived content, which can result in a diagnostic dilemma. Making an accurate diagnosis is essential for adequate management. CASE REPORT We present a case of a 39-year-old woman with past medical history of increased blood pressure, presenting with worsening headaches non-refractory to medication. Imaging revealed an extra-axial lesion within the midline posterior fossa with an occipital transdiploic linear channel. The lesion was T2 profoundly hypointense on brain MRI, and prominently hyperdense on non-contrast CT scan. Catheter angiography excluded vascular etiology. After complete lesion resection, results of the histopathologic examination were consistent with a dermoid cyst. Dermoid cysts that are hyperdense on CT and hypointense on T2-WI are extremely rare. CONCLUSIONS Complete surgical resection is the treatment of choice for most dermoid cysts. Atypical radiologic features, in an already rare intracranial tumor, can delay correct diagnosis and management. Recognition of these findings is therefore important for adequate imaging analysis of these lesions.
皮样囊肿是罕见的良性颅内肿瘤,通常具有典型的计算机断层扫描(CT)和磁共振成像(MRI)特征,易于做出诊断。由于其外胚层衍生的内容物多种多样,可能出现非典型影像学特征,从而导致诊断困难。准确诊断对于适当的治疗至关重要。
我们报告了一例 39 岁女性病例,既往有高血压病史,目前出现药物难治性头痛加重。影像学检查显示中线后颅窝的颅外病变,伴有枕骨板内线性通道。病变在脑 MRI 上 T2 呈明显低信号,非增强 CT 扫描呈显著高信号。导管血管造影排除血管性病因。在完成病变切除后,组织病理学检查结果与皮样囊肿一致。CT 呈高密度、T2-WI 呈低信号的皮样囊肿极为罕见。
大多数皮样囊肿的治疗选择是完全手术切除。在已经罕见的颅内肿瘤中,非典型的影像学特征可能会延迟正确的诊断和治疗。因此,对于这些病变的充分影像学分析,识别这些发现非常重要。