Cuproptosis: a new form of programmed cell death.
作者信息
Wang Yongqiang, Zhang Long, Zhou Fangfang
机构信息
Institutes of Biology and Medical Science, Soochow University, Suzhou, 215123, China.
MOE Laboratory of Biosystems Homeostasis and Protection and Innovation Center for Cell Signaling Network, Life Sciences Institute, Zhejiang University, Hangzhou, 310058, China.
出版信息
Cell Mol Immunol. 2022 Aug;19(8):867-868. doi: 10.1038/s41423-022-00866-1. Epub 2022 Apr 22.
Abstract
摘要
相似文献
1
Cuproptosis: a new form of programmed cell death.铜死亡：一种新的程序性细胞死亡形式。
Cell Mol Immunol. 2022 Aug;19(8):867-868. doi: 10.1038/s41423-022-00866-1. Epub 2022 Apr 22.
2
Cuproptosis: mechanisms and links with cancers.铜死亡：机制与癌症的关联。
Mol Cancer. 2023 Mar 7;22(1):46. doi: 10.1186/s12943-023-01732-y.
3
FDX1 enhances endometriosis cell cuproptosis via G6PD-mediated redox homeostasis.FDX1 通过 G6PD 介导的氧化还原平衡增强子宫内膜异位症细胞的铜死亡。
Apoptosis. 2023 Aug;28(7-8):1128-1140. doi: 10.1007/s10495-023-01845-1. Epub 2023 Apr 29.
4
Comprehensive investigation into cuproptosis in the characterization of clinical features, molecular characteristics, and immune situations of clear cell renal cell carcinoma.全面研究铜死亡在透明细胞肾细胞癌临床特征、分子特征和免疫状况中的作用。
Front Immunol. 2022 Oct 6;13:948042. doi: 10.3389/fimmu.2022.948042. eCollection 2022.
5
Stimulus-Responsive Copper Complex Nanoparticles Induce Cuproptosis for Augmented Cancer Immunotherapy.刺激响应型铜配合物纳米颗粒诱导铜死亡增强癌症免疫治疗。
Adv Sci (Weinh). 2024 Apr;11(13):e2309388. doi: 10.1002/advs.202309388. Epub 2024 Jan 25.
6
Comprehensive analysis of cuproptosis in immune response and prognosis of osteosarcoma.骨肉瘤免疫反应和预后中铜死亡的综合分析
Front Pharmacol. 2022 Oct 3;13:992431. doi: 10.3389/fphar.2022.992431. eCollection 2022.
7
EREG is the core onco-immunological biomarker of cuproptosis and mediates the cross-talk between VEGF and CD99 signaling in glioblastoma.EREG 是细胞铜死亡的核心免疫生物标志物，介导了胶质母细胞瘤中 VEGF 和 CD99 信号的串扰。
J Transl Med. 2023 Jan 16;21(1):28. doi: 10.1186/s12967-023-03883-4.
8
Identification of immune infiltration and cuproptosis-related subgroups in Crohn's disease.鉴定克罗恩病中的免疫浸润和铜死亡相关亚群。
Front Immunol. 2022 Nov 17;13:1074271. doi: 10.3389/fimmu.2022.1074271. eCollection 2022.
9
Copper-coordinated nanoassemblies based on photosensitizer-chemo prodrugs and checkpoint inhibitors for enhanced apoptosis-cuproptosis and immunotherapy.基于光敏剂-化疗前药和检查点抑制剂的铜协调纳米组装体用于增强细胞凋亡-铜死亡和免疫治疗。
Acta Biomater. 2024 Feb;175:341-352. doi: 10.1016/j.actbio.2023.12.022. Epub 2023 Dec 18.
10
A Novel Cuproptosis-Related Prognostic Gene Signature and Validation of Differential Expression in Clear Cell Renal Cell Carcinoma.一个新的铜死亡相关预后基因特征，并在透明细胞肾细胞癌中验证差异表达。
Genes (Basel). 2022 May 10;13(5):851. doi: 10.3390/genes13050851.
引用本文的文献
1
Identification of cuproptosis-related genes in chronic apical periodontitis based on bulk and single-cell RNA sequencing analyses and experimental validation.基于批量和单细胞RNA测序分析及实验验证鉴定慢性根尖周炎中与铜死亡相关的基因
Front Immunol. 2025 Aug 20;16:1559220. doi: 10.3389/fimmu.2025.1559220. eCollection 2025.
2
A biomimetic nanoplatform for multimodal imaging-guided therapy of esophageal cancer via synergistic activation of cuproptosis and ferroptosis.一种通过协同激活铜死亡和铁死亡实现多模态成像引导的食管癌治疗的仿生纳米平台。
Mater Today Bio. 2025 Aug 7;34:102178. doi: 10.1016/j.mtbio.2025.102178. eCollection 2025 Oct.
3
Comprehensive analysis of regulated cell death pathways: intrinsic disorder, protein-protein interactions, and cross-pathway communication.细胞程序性死亡途径的综合分析：内在无序、蛋白质-蛋白质相互作用及跨途径通讯
Apoptosis. 2025 Aug 19. doi: 10.1007/s10495-025-02161-6.
4
Plant programmed cell death in the context of diversity and evolution of PCD.在细胞程序性死亡的多样性与进化背景下的植物程序性细胞死亡
Protoplasma. 2025 Aug 15. doi: 10.1007/s00709-025-02102-9.
5
Mechanisms of copper metabolism and cuproptosis: implications for liver diseases.铜代谢与铜死亡的机制：对肝脏疾病的影响
Front Immunol. 2025 Jul 30;16:1633711. doi: 10.3389/fimmu.2025.1633711. eCollection 2025.
6
Engineered anti-cancer nanomedicine for synergistic cuproptosis-immunotherapy.用于协同铜死亡免疫治疗的工程化抗癌纳米药物
Mater Today Bio. 2025 Jul 29;34:102133. doi: 10.1016/j.mtbio.2025.102133. eCollection 2025 Oct.
7
Plumbagin Triggers Cuproptosis in Hepatocellular Carcinoma (HCC) via the DNA-Methyltransferase 1 (DNMT1)/microRNA-302a-3p (miR-302a-3p)/ATPase Copper Transporting Beta (ATP7B) Axis.白花丹醌通过DNA甲基转移酶1（DNMT1）/微小RNA-302a-3p（miR-302a-3p）/铜转运ATP酶β（ATP7B）轴引发肝细胞癌（HCC）中的铜死亡。
MedComm (2020). 2025 Aug 3;6(8):e70312. doi: 10.1002/mco2.70312. eCollection 2025 Aug.
8
Systemic Delivery Strategies for Oncolytic Viruses: Advancing Targeted and Efficient Tumor Therapy.溶瘤病毒的全身递送策略：推进靶向高效肿瘤治疗
Int J Mol Sci. 2025 Jul 18;26(14):6900. doi: 10.3390/ijms26146900.
9
Mitochondria as Regulators of Nonapoptotic Cell Death in Cancer.线粒体作为癌症中非凋亡性细胞死亡的调节因子。
MedComm (2020). 2025 Jul 23;6(8):e70244. doi: 10.1002/mco2.70244. eCollection 2025 Aug.
10
Identification and analysis of cuproptosis associated molecular clusters and immunological profiles in atopic dermatitis.特应性皮炎中铜死亡相关分子簇及免疫特征的鉴定与分析
Front Immunol. 2025 Jun 27;16:1545457. doi: 10.3389/fimmu.2025.1545457. eCollection 2025.
本文引用的文献
1
Copper induces cell death by targeting lipoylated TCA cycle proteins.铜通过靶向脂酰化 TCA 循环蛋白诱导细胞死亡。
Science. 2022 Mar 18;375(6586):1254-1261. doi: 10.1126/science.abf0529. Epub 2022 Mar 17.
2
Mitochondria as multifaceted regulators of cell death.线粒体作为细胞死亡的多面调节者。
Nat Rev Mol Cell Biol. 2020 Feb;21(2):85-100. doi: 10.1038/s41580-019-0173-8. Epub 2019 Oct 21.
3
Mitochondrial metabolism promotes adaptation to proteotoxic stress.线粒体代谢促进适应蛋白毒性应激。
Nat Chem Biol. 2019 Jul;15(7):681-689. doi: 10.1038/s41589-019-0291-9. Epub 2019 May 27.
4
Ferroptosis: an iron-dependent form of nonapoptotic cell death.铁死亡：一种依赖于铁的非细胞凋亡性细胞死亡形式。
Cell. 2012 May 25;149(5):1060-72. doi: 10.1016/j.cell.2012.03.042.
5
The oncology drug elesclomol selectively transports copper to the mitochondria to induce oxidative stress in cancer cells.肿瘤药物依立替康选择性地将铜运输到线粒体，在癌细胞中诱导氧化应激。
Free Radic Biol Med. 2012 May 15;52(10):2142-50. doi: 10.1016/j.freeradbiomed.2012.03.017. Epub 2012 Apr 17.
Zotero 插件