Taylor J J
Haematologia (Budap). 1986;19(4):269-73.
A patient is described with hypercalcaemia due to myelomatosis without paraproteinaemia or Bence-Jones proteinuria. Immunological investigations yielded some evidence of intra-cellular immunoglobulin production. Histological features suggested the secretion of osteoclast activating factor. Relevant experimental work in support of this interpretation is reviewed.
本文描述了一名因骨髓瘤病导致高钙血症的患者,该患者无副蛋白血症或本周氏蛋白尿。免疫学检查发现了一些细胞内免疫球蛋白产生的证据。组织学特征提示破骨细胞活化因子的分泌。本文回顾了支持这一解释的相关实验工作。