Department of Anatomy, Kyorin University School of Medicine, 6-20-2 Shinkawa, Mitaka, Tokyo, 181-8611, Japan.
Kunitachi Aoyagien Tachikawa Geriatric Health Services Facility, Tokyo, Japan.
Anat Sci Int. 2022 Jul;97(3):273-282. doi: 10.1007/s12565-022-00664-9. Epub 2022 Apr 22.
The traditional apprenticeship approach to surgical skill education for young surgeons has drastically changed to more systematic surgical training using cadavers. Cadavers fixed with formalin are not suitable for surgical training because of their associated health hazards and overhardening. Recently, we established a formalin-free soft preservation method for human cadavers using N-vinyl-2-pyrrolidone. Since 2012, 61 cadavers have been embalmed with pyrrolidone in our institution. Tissues of pyrrolidone-embalmed cadavers are soft and pliable, and their bodies can be preserved for as long as 37 months without any signs of corruption. In this review, we introduce our recent attempts to apply pyrrolidone-embalmed cadavers in surgical and medical procedure training, including endotracheal intubation, motion physiology of the vocal folds, laparoscopic surgery, endoscopic skull base surgery, and development of novel medical devices. Future research perspectives on pyrrolidone embalming are discussed.
传统的学徒制方法已经彻底改变了年轻外科医生的手术技能教育，更多地采用尸体进行更系统的外科培训。由于福尔马林固定的尸体存在相关的健康危害和过度硬化，因此不适合用于手术培训。最近，我们使用 N-乙烯基-2-吡咯烷酮建立了一种福尔马林免费的人体尸体软保存方法。自 2012 年以来，我们机构已经使用吡咯烷酮对 61 具尸体进行了防腐处理。吡咯烷酮处理的尸体组织柔软有弹性，其身体可以保存长达 37 个月而不会出现腐败迹象。在这篇综述中，我们介绍了我们最近尝试将吡咯烷酮处理的尸体应用于手术和医疗程序培训，包括气管插管、声带运动生理学、腹腔镜手术、内镜颅底手术和新型医疗器械的开发。讨论了吡咯烷酮防腐的未来研究展望。
