氧氟沙星与环丙沙星治疗复杂性尿路感染的临床评估（原文中多了一个of，应改为正确表述）

Clinical evaluation of ofloxacin versus ciprofloxacin in complicated urinary tract infections.

作者信息

Kromann-Andersen B, Sommer P, Pers C, Larsen V, Rasmussen F

出版信息

Infection. 1986;14 Suppl 4:S305-6. doi: 10.1007/BF01661301.

Abstract

Ofloxacin was administered to 18 patients and ciprofloxacin to 17 patients suffering from acute or chronic complicated urinary tract infections. Patients received doses of 100 mg ofloxacin, b.i.d., or 250 mg ciprofloxacin, b.i.d., for seven days. The clinical and bacteriological response were evaluated after 17 days. Resolution of symptoms were found in approximately 60% of cases for both treatments and bacteriological eradication was 66% for ofloxacin and 50% for ciprofloxacin. Side-effects such as itching and rash were reported in three cases. The results indicate that ofloxacin and ciprofloxacin are safe and effective agents in the treatment of complicated urinary tract infections.

摘要

18例患有急性或慢性复杂性尿路感染的患者接受了氧氟沙星治疗，17例患者接受了环丙沙星治疗。患者接受100毫克氧氟沙星，每日两次，或250毫克环丙沙星，每日两次，持续7天。17天后评估临床和细菌学反应。两种治疗方法在大约60%的病例中症状得到缓解，氧氟沙星的细菌清除率为66%，环丙沙星为50%。有3例报告了瘙痒和皮疹等副作用。结果表明，氧氟沙星和环丙沙星是治疗复杂性尿路感染的安全有效药物。