Liu Tianshu, Shi Jiawei, Fu Yanan, Zhang Yichan, Bai Ying, He Shukun, Deng Wenhui, Jin Qiaofeng, Chen Yihan, Fang Lingyun, He Lin, Li Yuman, Yang Yali, Zhang Li, Lv Qing, Wang Jing, Xie Mingxing
Department of Ultrasound Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China; Hubei Province Clinical Research Center for Medical Imaging, Wuhan 430022, China; Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China.
Department of Ultrasound Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China; Hubei Province Clinical Research Center for Medical Imaging, Wuhan 430022, China; Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China.
Trends Cardiovasc Med. 2023 Oct;33(7):431-440. doi: 10.1016/j.tcm.2022.04.005. Epub 2022 Apr 21.
Significant advances in application of therapeutic ultrasound have been reported in the past decades. Therapeutic ultrasound is an emerging non-invasive stimulation technique. This approach has shown high potential for treatment of various disease including cardiovascular disease. In this review, application principle and significance of the basic parameters of therapeutic ultrasound are summarized. The effects of therapeutic ultrasound in myocardial ischemia, heart failure, myocarditis, arrhythmias, and hypertension are explored, with key focus on the underlying mechanism. Further, the limitations and challenges of ultrasound therapy on clinical translation are evaluated to promote application of the novel strategy in cardiovascular diseases.
在过去几十年中，治疗性超声的应用取得了重大进展。治疗性超声是一种新兴的非侵入性刺激技术。这种方法在治疗包括心血管疾病在内的各种疾病方面显示出巨大潜力。在本综述中，总结了治疗性超声基本参数的应用原理及意义。探讨了治疗性超声在心肌缺血、心力衰竭、心肌炎、心律失常和高血压中的作用，重点关注其潜在机制。此外，评估了超声治疗在临床转化方面的局限性和挑战，以促进这一新技术在心血管疾病中的应用。
