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正在进行的患者随机分组:医学护理研究中的一项创新。

Ongoing patient randomization: an innovation in medical care research.

作者信息

Cargill V, Cohen D, Kroenke K, Neuhauser D

出版信息

Health Serv Res. 1986 Dec;21(5):663-78.

PMID:3546202
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1068980/
Abstract

Hospitals often have rotational assignment of patients to one of several similar provider care teams. The research potential of these arrangements has gone unnoticed. By changing to random assignment of patients and physicians to provider care teams (firms) this kind of organization can be used for sequential, randomized clinical trials which are ethical and efficient. The paper describes such arrangements at three different hospitals: Cleveland Metropolitan General Hospital, Brooke Army Medical Center, and University Hospitals of Cleveland. Associated methodologic issues are discussed. This is a new, more widely applicable method for medical care research.

摘要

医院常常将患者轮流分配到几个类似的医疗服务团队中的一个。这些安排的研究潜力一直未被关注。通过将患者和医生随机分配到医疗服务团队(公司),这种组织形式可用于进行符合伦理且高效的序贯随机临床试验。本文描述了克利夫兰市立综合医院、布鲁克陆军医疗中心和克利夫兰大学医院这三家不同医院的此类安排。文中还讨论了相关的方法学问题。这是一种新的、更广泛适用的医疗研究方法。

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本文引用的文献

1
The treatment of acute infectious hepatitis. Controlled studies of the effects of diet, rest, and physical reconditioning on the acute course of the disease and on the incidence of relapses and residual abnormalities.急性传染性肝炎的治疗。关于饮食、休息和身体恢复对疾病急性病程、复发率及残留异常发生率影响的对照研究。
J Clin Invest. 1955 Jul;34(7, Part II):1163-235. doi: 10.1172/JCI103164.
2
Randomized field experiments for program planning, development, and evaluation: an illustrative bibliography.用于项目规划、开发和评估的随机实地实验:一份示例书目。
Eval Q. 1978 Nov;2(4):655-95. doi: 10.1177/0193841x7800200411.
3
MEU: measuring efficient utilization of hospital services.MEU:衡量医院服务的有效利用情况
Health Care Manage Rev. 1976 Spring;1(2):63-70. doi: 10.1097/00004010-197600120-00009.
4
A trial of two strategies to modify the test-ordering behavior of medical residents.一项关于两种策略以改变住院医师开检查单行为的试验。
N Engl J Med. 1980 Dec 4;303(23):1330-6. doi: 10.1056/NEJM198012043032304.
5
Improving physician compliance with preventive medicine guidelines.提高医生对预防医学指南的依从性。
Med Care. 1982 Oct;20(10):1040-5. doi: 10.1097/00005650-198210000-00006.
6
Does cost information availability reduce physician test usage? A randomized clinical trial with unexpected findings.
Med Care. 1982 Mar;20(3):286-92. doi: 10.1097/00005650-198203000-00005.
7
The natural history of intravenous catheter-associated phlebitis.静脉导管相关静脉炎的自然病程。
Arch Intern Med. 1984 Jul;144(7):1373-5.
8
Choosing the correct unit of analysis in Medical Care experiments.在医疗保健实验中选择正确的分析单位。
Med Care. 1984 Dec;22(12):1101-14. doi: 10.1097/00005650-198412000-00005.
9
Intravenous therapy team and peripheral venous catheter-associated complications. A prospective controlled study.静脉治疗团队与外周静脉导管相关并发症。一项前瞻性对照研究。
Arch Intern Med. 1984 Jun;144(6):1191-4.
10
Influence of simple computerized feedback on prescription charges in an ambulatory clinic. A randomized clinical trial.
Med Care. 1986 Jun;24(6):472-81. doi: 10.1097/00005650-198606000-00002.