Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
Cancer. 2014 Jun 15;120(12):1763-74. doi: 10.1002/cncr.28657. Epub 2014 Mar 19.
The 2013 World Health Organization Classification of Tumors of Soft Tissue and Bone incorporates changes in tumor classification, as well as new genetic insights into the pathogenesis of many different tumor types that have emerged over the 11 years since the publication of the prior volume. This article reviews changes in the classification of soft tissue and bone sarcomas as well as tumors of intermediate biologic potential in the 2013 World Health Organization volume, new molecular insights into these tumors, and associated surgical and clinical implications.
2013 年世界卫生组织软组织和骨肿瘤分类结合了肿瘤分类的变化,以及自前一版出版以来 11 年来许多不同肿瘤类型发病机制的新遗传见解。本文回顾了 2013 年世界卫生组织卷中软组织和骨肉瘤以及中间生物学潜能肿瘤分类的变化,这些肿瘤的新分子见解,以及相关的手术和临床意义。