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本文引用的文献

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World Health Organization, radiofrequency radiation and health - a hard nut to crack (Review).世界卫生组织、射频辐射与健康——一个棘手的问题（综述）。
Int J Oncol. 2017 Aug;51(2):405-413. doi: 10.3892/ijo.2017.4046. Epub 2017 Jun 21.
2
Survey on Different Samsung with Nokia Smart Mobile Phones in the Specific Absorption Rate Electrical Field of Head.头部特定吸收率电场中不同三星与诺基亚智能手机的调查。
Glob J Health Sci. 2016 Sep 1;8(9):53967. doi: 10.5539/gjhs.v8n9p251.
3
Effect of mobile phone usage time on total antioxidant capacity of saliva and salivary immunoglobulin a.手机使用时间对唾液总抗氧化能力和唾液免疫球蛋白A的影响。
Iran J Public Health. 2014 Apr;43(4):480-4.
4
Effect of cell phone use on salivary total protein, enzymes and oxidative stress markers in young adults: a pilot study.手机使用对年轻成年人唾液总蛋白、酶及氧化应激标志物的影响：一项初步研究。
J Clin Diagn Res. 2015 Feb;9(2):BC19-22. doi: 10.7860/JCDR/2015/10872.5580. Epub 2015 Feb 1.
5
Effect of mobile phone use on salivary concentrations of protein, amylase, lipase, immunoglobulin A, lysozyme, lactoferrin, peroxidase and C-reactive protein of the parotid gland.手机使用对腮腺唾液中蛋白质、淀粉酶、脂肪酶、免疫球蛋白A、溶菌酶、乳铁蛋白、过氧化物酶和C反应蛋白浓度的影响。
J Laryngol Otol. 2014 May;128(5):454-62. doi: 10.1017/S0022215114000899. Epub 2014 Apr 17.
6
Is human saliva an indicator of the adverse health effects of using mobile phones?使用手机对健康的不良影响可通过唾液反映出来吗？
Antioxid Redox Signal. 2013 Feb 20;18(6):622-7. doi: 10.1089/ars.2012.4751. Epub 2012 Oct 9.
7
Effect of handheld mobile phone use on parotid gland salivary flow rate and volume.手持移动电话使用对腮腺唾液流率和体积的影响。
Oral Surg Oral Med Oral Pathol Oral Radiol. 2012 Aug;114(2):200-6. doi: 10.1016/j.oooo.2012.03.001.
8
The influence of handheld mobile phones on human parotid gland secretion.手持移动电话对人腮腺分泌的影响。
Oral Dis. 2010 Mar;16(2):146-50. doi: 10.1111/j.1601-0825.2009.01620.x. Epub 2009 Sep 8.
9
The influence of the call with a mobile phone on heart rate variability parameters in healthy volunteers.手机通话对健康志愿者心率变异性参数的影响。
Ind Health. 2008 Aug;46(4):409-17. doi: 10.2486/indhealth.46.409.
10
Role of free radicals and antioxidants in the pathogenesis of the inflammatory periodontal diseases.自由基和抗氧化剂在炎症性牙周疾病发病机制中的作用。
Clin Mol Pathol. 1996 Oct;49(5):M247-55. doi: 10.1136/mp.49.5.m247.

手机使用时长对唾液流量、唾液总抗氧化能力及唾液免疫球蛋白A水平的影响：一项横断面研究

Effect of Duration of Mobile Phone Use on the Salivary Flow and Total Antioxidant Capacity of Saliva and Salivary Immunoglobulin A Level: A Cross-sectional Study.

作者信息

Bansal Divyansh, Chhaparwal Yogesh, Pai Keerthilatha M, Kumar Mathangi, Vineetha Ravindranath, Chhaparwal Shubha, Kamath Shobha, Kamath Asha

机构信息

Department of Oral Medicine and Radiology, Manipal College of Dental Sciences, Manipal, India.

Department of Conservative Dentistry and Endodontics, Manipal College of Dental Sciences, Manipal, India.

出版信息

J Int Soc Prev Community Dent. 2022 Apr 8;12(2):260-265. doi: 10.4103/jispcd.JISPCD_361_21. eCollection 2022 Mar-Apr.

DOI:10.4103/jispcd.JISPCD_361_21
PMID:35462741
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9022387/
Abstract

INTRODUCTION

The objective of this study was to observe the effects of the duration of handheld mobile phone usage on the salivary flow, salivary immunoglobulin A (IgA) level, and salivary markers for oxidative stress.

MATERIALS AND METHODS

Eighty-one students were categorized into three groups based on their duration of mobile phone usage after age- and gender-matching. Students were grouped as: mobile phone usage <20 min/day (Group A), mobile phone usage 20-60 min/day (Group B), and mobile phone usage >60 min/day (Group C). Saliva was collected to evaluate salivary flow rate, salivary IgA level, and salivary markers for oxidative stress.

RESULTS

The salivary flow rate showed no statistically significant difference between the three groups ( = 0.180). There was no statistically significant difference in the salivary IgA between the three groups ( = 0.237). There was a statistically significant difference in the malondialdehyde (MDA) level between the three groups ( = 0.042). On pair comparison between the groups, group B and group C had a statistically significant difference ( = 0.019) in the MDA level. There was no statistically significant difference in the salivary thiol level between the three groups ( = 0.237).

CONCLUSION

The duration of handheld mobile phone usage did not show any significant effects on the salivary flow rate, salivary IgA, and thiol levels. There was an increase in the salivary MDA concentration in subjects using handheld mobile phones for a longer duration, indicating higher oxidative stress in salivary glands exposed to mobile phone radiofrequency electromagnetic waves for a longer duration.

摘要

引言

本研究的目的是观察手持移动电话使用时长对唾液流量、唾液免疫球蛋白A（IgA）水平以及氧化应激唾液标志物的影响。

材料与方法

81名学生在进行年龄和性别匹配后，根据其移动电话使用时长分为三组。学生分组如下：移动电话使用时长<20分钟/天（A组），移动电话使用时长20 - 60分钟/天（B组），移动电话使用时长>60分钟/天（C组）。收集唾液以评估唾液流速、唾液IgA水平以及氧化应激唾液标志物。

结果

三组之间的唾液流速无统计学显著差异（P = 0.180）。三组之间的唾液IgA无统计学显著差异（P = 0.237）。三组之间的丙二醛（MDA）水平有统计学显著差异（P = 0.042）。在组间两两比较中，B组和C组的MDA水平有统计学显著差异（P = 0.019）。三组之间的唾液硫醇水平无统计学显著差异（P = 0.237）。

结论

手持移动电话的使用时长对唾液流速、唾液IgA和硫醇水平未显示出任何显著影响。使用手持移动电话时长较长的受试者唾液MDA浓度升高，表明唾液腺在较长时间暴露于移动电话射频电磁波下会产生更高的氧化应激。