手机使用对年轻成年人唾液总蛋白、酶及氧化应激标志物的影响：一项初步研究。
Effect of cell phone use on salivary total protein, enzymes and oxidative stress markers in young adults: a pilot study.
作者信息
Shivashankara Arnadi Ramachandrayya, Joy Jasmi, Sunitha Venkatesh, Rai Manoj P, Rao Suresh, Nambranathayil Shafeeque, Baliga Manjeshwar Shrinath
机构信息
Associate Professor, Department of Biochemistry, Father Muller Medical College , Mangalore, India .
Research Scholar, Father Muller Research Centre , Kankanady, Mangalore, India .
出版信息
J Clin Diagn Res. 2015 Feb;9(2):BC19-22. doi: 10.7860/JCDR/2015/10872.5580. Epub 2015 Feb 1.
INTRODUCTION
The present study aimed to assess the levels of salivary enzymes, protein and oxidant-antioxidant system in young college-going cell phone users.
MATERIALS AND METHODS
The cell users (students) were categorized in to two groups - less mobile users and high mobile users, based on the duration and frequency of cell use. Unstimulated whole saliva samples of the volunteers were analysed for amylase, lactate dehydrogenase (LDH), malondialdehdye (MDA) and glutathione (GSH).
RESULTS
High mobile users had significantly higher levels of amylase (p = 0.001), LDH (p = 0.002) and MDA (p = 0.002) in saliva, when compared to less mobile users. The marginal decrease in salivary total proteins, GSH and flow rate were statistically not significant (p >0.05).
CONCLUSION
Significant changes in salivary enzymes and MDA suggest adverse effect of high use of cell phones on cell health.
引言
本研究旨在评估年轻的大学生手机用户唾液中的酶、蛋白质以及氧化-抗氧化系统水平。
材料与方法
根据手机使用时长和频率，将手机用户（学生）分为两组——低手机使用量用户和高手机使用量用户。对志愿者的非刺激性全唾液样本进行淀粉酶、乳酸脱氢酶（LDH）、丙二醛（MDA）和谷胱甘肽（GSH）分析。
结果
与低手机使用量用户相比，高手机使用量用户唾液中的淀粉酶（p = 0.001）、LDH（p = 0.002）和MDA（p = 0.002）水平显著更高。唾液总蛋白、GSH和流速的轻微下降在统计学上无显著意义（p >0.05）。
结论
唾液酶和MDA的显著变化表明高频率使用手机对细胞健康有不良影响。
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