Wang Yunan, Wang Hairui, Liu Zhaoyu, Chang Zhihui
Department of Radiology, Shengjing Hospital of China Medical University, Shenyang, China.
Gastroenterol Res Pract. 2022 Apr 15;2022:3777122. doi: 10.1155/2022/3777122. eCollection 2022.
: Septic pulmonary embolism (SPE) is an associated complication of liver abscess (KPLA). However, previous studies have reported that its incidence varies widely. We conducted a systematic review and meta-analysis to investigate the incidence of SPE in patients with KPLA. We further analyzed their clinical and computed tomography (CT) features. : Two researchers reviewed PubMed, EMBASE, Web of Science, and Cochrane Library databases to identify the articles that reported SPE in patients with KPLA. The search was conducted from the date of establishment of each database up to January 2021. After screening the articles and extracting the data, we used Review Manager 5.3 for analysis and processing. : We selected six articles that included 1,158 patients with KPLA. Of these, 70 patients had SPE. The pooled incidence of SPE was 6% (95% confidence interval, 3%-9%). Among patients with SPE, 85% were men, 72% had diabetes, and 52% displayed the feeding vessel sign on the chest CT. The mortality rate was 12%. Quality assessment revealed that half of the included studies had a high quality. : The pooled incidence of SPE in patients with KPLA was 6%. Men and patients with diabetes were more prone to SPE. For patients with KPLA who had SPE as an associated complication, the mortality rate was approximately 12%.
脓毒性肺栓塞（SPE）是肝脓肿（KPLA）的一种相关并发症。然而，既往研究报道其发病率差异很大。我们进行了一项系统评价和荟萃分析，以调查KPLA患者中SPE的发病率。我们还进一步分析了其临床和计算机断层扫描（CT）特征。
两名研究人员检索了PubMed、EMBASE、Web of Science和Cochrane图书馆数据库，以识别报道KPLA患者中SPE的文章。检索从每个数据库建立之日起至2021年1月进行。在筛选文章并提取数据后，我们使用Review Manager 5.3进行分析和处理。
我们选择了6篇文章，共纳入1158例KPLA患者。其中，70例患者发生了SPE。SPE的合并发病率为6%（95%置信区间，3%-9%）。在发生SPE的患者中，85%为男性，72%患有糖尿病，52%在胸部CT上显示供血血管征。死亡率为12%。质量评估显示，纳入研究中有一半质量较高。
KPLA患者中SPE的合并发病率为6%。男性和糖尿病患者更容易发生SPE。对于发生SPE这一相关并发症的KPLA患者，死亡率约为12%。
