肾母细胞瘤病例中化疗联合手术治疗
Chemotherapy Combined With Surgery in a Case With Metanephric Adenoma.
作者信息
Hu Shaohua, Zhao Zhenli, Wan Zhisheng, Bu Weizhen, Chen Songqiang, Lu Yiqun
机构信息
Department of Urology, Hainan Women and Children's Medical Center, Haikou, China.
Department of Urology, Children's Hospital of Fudan University, Shanghai, China.
出版信息
Front Pediatr. 2022 Apr 7;10:847864. doi: 10.3389/fped.2022.847864. eCollection 2022.
BACKGROUND
Metanephric adenoma is an extremely rare renal neoplasm, especially in pediatrics. Chemotherapy combined with surgery in metanephric adenoma has not been reported.
METHODS
We describe a case of metanephric adenoma in a child less than 2 years old, which were treated by chemotherapy combined with surgery.
RESULTS
Nephron sparing surgery was performed after regular chemotherapy, and the pathological result was metanephric adenoma.
CONCLUSION
Pediatric metanephric adenoma is extremely rare; the clinical manifestations and imaging examinations lack specificity. Nephron sparing surgery is recommended as the preferred treatment for metanephric adenoma. Long-term follow-up and more in-depth molecular genetic research are still needed to determine the benign or malignant of metanephric adenoma and whether chemotherapy drugs have an effect on it.
背景
后肾腺瘤是一种极其罕见的肾脏肿瘤，在儿科尤为少见。后肾腺瘤化疗联合手术治疗尚未见报道。
方法
我们描述了1例年龄小于2岁的儿童后肾腺瘤，采用化疗联合手术治疗。
结果
经过规律化疗后行保留肾单位手术，病理结果为后肾腺瘤。
结论
小儿后肾腺瘤极为罕见；临床表现及影像学检查缺乏特异性。推荐保留肾单位手术作为后肾腺瘤的首选治疗方式。仍需要长期随访及更深入的分子遗传学研究以明确后肾腺瘤的良恶性及化疗药物对其是否有效。
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