Akman Canan, Bardakçı Okan, Daş Murat, Akdur Gökhan, Akdur Okhan
Emergency Department, Canakkale Onsekiz Mart University Faculty of Medicine, Canakkale, TUR.
Cureus. 2022 Mar 9;14(3):e23012. doi: 10.7759/cureus.23012. eCollection 2022 Mar.
As the mortality rate in coronavirus disease 2019 (COVID-19) patients older than 65 years is considerable, evaluation of in-hospital mortality is crucial. This study aimed to evaluate in-hospital mortality in COVID-19 patients older than 65 years using the National Early Warning Score (NEWS), Quick Sequential Organ Failure Assessment (q-SOFA), Charlson Comorbidity Index (CCI), and Elixhauser Comorbidity Index (ECI).
This retrospective study included data from 480 patients with confirmed COVID-19 and age over 65 years who were evaluated in a university emergency department in Turkey. Data from eligible but deceased COVID-19 patients was also included. NEWS, q-SOFA, CCI, and ECI scores were retrospectively calculated. All clinical data was accessed from the information management system of the hospital, retrieved, and analyzed.
In-hospital mortality was seen in 169 patients (169/480). Low oxygen saturation, high C-reactive protein (CRP) and urea levels, and high q-SOFA and ECI scores helped us identify mortality in high-risk patients. A statistically significant difference was found in mortality estimation between q-SOFA and ECI (p <0.001), respectively.
Q-SOFA and ECI can be used both easily and practically in the early diagnosis of in-hospital mortality in COVID-19 positive patients over 65 years of age admitted to the emergency department. Low oxygen saturation, high CRP and urea levels, and high q-SOFA and ECI scores are helpful in identifying high-risk patients.
由于2019冠状病毒病(COVID-19)65岁以上患者的死亡率相当高,因此评估住院死亡率至关重要。本研究旨在使用国家早期预警评分(NEWS)、快速序贯器官衰竭评估(q-SOFA)、查尔森合并症指数(CCI)和埃利克斯豪泽合并症指数(ECI)来评估65岁以上COVID-19患者的住院死亡率。
这项回顾性研究纳入了在土耳其一所大学急诊科接受评估的480例确诊COVID-19且年龄超过65岁患者的数据。还纳入了符合条件但已死亡的COVID-19患者的数据。对NEWS、q-SOFA、CCI和ECI评分进行回顾性计算。所有临床数据均从医院的信息管理系统中获取、检索并分析。
169例患者(169/480)出现住院死亡。低氧饱和度、高C反应蛋白(CRP)和尿素水平以及高q-SOFA和ECI评分有助于我们识别高危患者的死亡情况。q-SOFA和ECI在死亡率估计方面分别存在统计学显著差异(p<0.001)。
Q-SOFA和ECI可简便、实用地用于急诊科收治的65岁以上COVID-19阳性患者住院死亡率的早期诊断。低氧饱和度、高CRP和尿素水平以及高q-SOFA和ECI评分有助于识别高危患者。