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国家早期预警评分、快速序贯器官衰竭评估、查尔森合并症指数和埃利克斯豪泽合并症指数评分在预测老年患者因 COVID-19 导致的死亡率方面的有效性。

The Effectiveness of National Early Warning Score, Quick Sequential Organ Failure Assessment, Charlson Comorbidity Index, and Elixhauser Comorbidity Index Scores in Predicting Mortality Due to COVID-19 in Elderly Patients.

作者信息

Akman Canan, Bardakçı Okan, Daş Murat, Akdur Gökhan, Akdur Okhan

机构信息

Emergency Department, Canakkale Onsekiz Mart University Faculty of Medicine, Canakkale, TUR.

出版信息

Cureus. 2022 Mar 9;14(3):e23012. doi: 10.7759/cureus.23012. eCollection 2022 Mar.

Abstract

INTRODUCTION

As the mortality rate in coronavirus disease 2019 (COVID-19) patients older than 65 years is considerable, evaluation of in-hospital mortality is crucial. This study aimed to evaluate in-hospital mortality in COVID-19 patients older than 65 years using the National Early Warning Score (NEWS), Quick Sequential Organ Failure Assessment (q-SOFA), Charlson Comorbidity Index (CCI), and Elixhauser Comorbidity Index (ECI).

METHODS

This retrospective study included data from 480 patients with confirmed COVID-19 and age over 65 years who were evaluated in a university emergency department in Turkey. Data from eligible but deceased COVID-19 patients was also included. NEWS, q-SOFA, CCI, and ECI scores were retrospectively calculated. All clinical data was accessed from the information management system of the hospital, retrieved, and analyzed.

RESULTS

In-hospital mortality was seen in 169 patients (169/480). Low oxygen saturation, high C-reactive protein (CRP) and urea levels, and high q-SOFA and ECI scores helped us identify mortality in high-risk patients. A statistically significant difference was found in mortality estimation between q-SOFA and ECI (p <0.001), respectively.

CONCLUSION

Q-SOFA and ECI can be used both easily and practically in the early diagnosis of in-hospital mortality in COVID-19 positive patients over 65 years of age admitted to the emergency department. Low oxygen saturation, high CRP and urea levels, and high q-SOFA and ECI scores are helpful in identifying high-risk patients.

摘要

引言

由于2019冠状病毒病(COVID-19)65岁以上患者的死亡率相当高,因此评估住院死亡率至关重要。本研究旨在使用国家早期预警评分(NEWS)、快速序贯器官衰竭评估(q-SOFA)、查尔森合并症指数(CCI)和埃利克斯豪泽合并症指数(ECI)来评估65岁以上COVID-19患者的住院死亡率。

方法

这项回顾性研究纳入了在土耳其一所大学急诊科接受评估的480例确诊COVID-19且年龄超过65岁患者的数据。还纳入了符合条件但已死亡的COVID-19患者的数据。对NEWS、q-SOFA、CCI和ECI评分进行回顾性计算。所有临床数据均从医院的信息管理系统中获取、检索并分析。

结果

169例患者(169/480)出现住院死亡。低氧饱和度、高C反应蛋白(CRP)和尿素水平以及高q-SOFA和ECI评分有助于我们识别高危患者的死亡情况。q-SOFA和ECI在死亡率估计方面分别存在统计学显著差异(p<0.001)。

结论

Q-SOFA和ECI可简便、实用地用于急诊科收治的65岁以上COVID-19阳性患者住院死亡率的早期诊断。低氧饱和度、高CRP和尿素水平以及高q-SOFA和ECI评分有助于识别高危患者。

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