McDonald W S, Deitch E A
J Trauma. 1987 Feb;27(2):147-50. doi: 10.1097/00005373-198702000-00008.
A prospective study of 70 consecutive burned patients, 26 pediatric patients and 44 adults, who had 173 separate anatomic sites grafted, was carried out to determine the incidence of hypertrophic skin grafts after thermal injury. The age, race, postburn day grafted, anatomic site grafted, and nature of the recipient graft bed was recorded. The patients were followed for a minimum of 1 year, at which time the skin grafts were classified as Excellent (E)--skin graft flat and not thickened; Good (G)--less than 5% of skin graft thickened or elevated; Fair (F)--greater than 5% of skin graft thickened or elevated; and Poor (P)--skin graft elevated greater than 2 mm or contracture present. Overall, 55% of the grafted sites were excellent, 18% were good, 13% were fair, and 14% were poor. Pediatric patients had a higher incidence of fair or poor results (50%) than adults (17%) (p less than 0.001), and blacks had poorer (39% F or P) results than whites (12% F or P) (p less than 0.001). The presence of dermal elements in the recipient graft bed was associated with less long-term skin graft scarring than when the grafts were placed on recipient beds without dermal elements (p less than 0.01). Skin grafts that were performed within 14 days of the injury had a lower incidence of F or P results (24%), than grafts performed after 14 days postburn (37%) (p less than 0.03). Based on the results of this prospective study, it is possible to identify and quantitate the relative risk of a burned patient developing a hypertrophic skin graft.
对70例连续烧伤患者进行了一项前瞻性研究,其中包括26例儿科患者和44例成人患者,这些患者共有173个不同的解剖部位接受了植皮,以确定热损伤后肥厚性皮肤移植的发生率。记录了患者的年龄、种族、烧伤后植皮日期、植皮的解剖部位以及受区植皮床的性质。对患者进行了至少1年的随访,此时将皮肤移植分为优秀(E)——皮肤移植平整且未增厚;良好(G)——皮肤移植增厚或隆起少于5%;一般(F)——皮肤移植增厚或隆起大于5%;差(P)——皮肤移植隆起大于2mm或存在挛缩。总体而言:55%的植皮部位为优秀,18%为良好,13%为一般,14%为差。儿科患者的一般或差结果发生率(50%)高于成人(17%)(p<0.001),黑人的结果(39%为F或P)比白人(12%为F或P)差(p<0.001)。与将移植物置于无真皮成分的受区相比,受区植皮床中存在真皮成分与长期皮肤移植瘢痕形成较少相关(p<0.01)。在受伤后14天内进行的皮肤移植,F或P结果的发生率(24%)低于烧伤后14天以后进行的移植(37%)(p<0.03)。基于这项前瞻性研究的结果,可以识别和量化烧伤患者发生肥厚性皮肤移植的相对风险。