Shanghai Engineering Research Center of Green Energy Chemical Engineering, College of Chemistry and Materials Science, Shanghai Normal University, 100 Guilin Road, Shanghai 200234, P. R. China.
Shanghai Key Laboratory of Protection Horticultural Technology, Eco-Environmental Protection Research Institute, Shanghai Academy of Agricultural Sciences, Shanghai 201403, P. R. China.
J Agric Food Chem. 2022 May 4;70(17):5310-5318. doi: 10.1021/acs.jafc.1c08182. Epub 2022 Apr 25.
The utilization of intelligent controlled release technology to create stimuli-responsive pesticide formulations has been shown to effectively improve pesticide efficacy and reduce environmental pollution. Herein, a glutathione-responsive release polyurea (PU) microcapsules (MCs) loaded with pyraclostrobin were developed via the interface polymerization method. The pyraclostrobin-loaded PU-MCs showed a regular spherical shape with an average diameter of 480 nm. It also showed good thermal stability and rheological properties. Furthermore, the pyraclostrobin-loaded PU-MCs exhibited favorable wettability on wheat leaves, which was beneficial for enhancing the retention capacity of pesticide droplets and improving pesticide utilization. The pyraclostrobin can be released from MCs and directly proportional to glutathione (GSH) concentrations with Fickian diffusion. Importantly, the control efficacy of pyraclostrobin-loaded PU-MCs against was positively correlated with GSH, indicating a promising candidate for a controlled release of pesticides in agriculture and laying the foundation for further field experiments.
利用智能控制释放技术来制备对刺激响应的农药制剂已被证明可以有效地提高农药的功效并减少环境污染。在此，通过界面聚合法制备了载有吡唑醚菌酯的谷胱甘肽响应型释放型聚脲（PU）微胶囊（MCs）。载有吡唑醚菌酯的 PU-MC 呈规则的球形，平均直径为 480nm。它还表现出良好的热稳定性和流变性能。此外，载有吡唑醚菌酯的 PU-MC 在小麦叶片上表现出良好的润湿性，有利于提高农药液滴的保持能力并提高农药利用率。吡唑醚菌酯可以从 MC 中释放出来，并与谷胱甘肽（GSH）浓度呈比例关系，符合菲克扩散定律。重要的是，载有吡唑醚菌酯的 PU-MC 对 的防治效果与 GSH 呈正相关，这表明它是农业中控制释放农药的有前途的候选物，为进一步的田间试验奠定了基础。
