Raybin Jennifer L, Zhou Wenru, Pan Zhaoxing, Jankowski Catherine
Pediatric Palliative Care, Center for Cancer and Blood Disorders, Pediatrics, Children's Hospital Colorado, University of Colorado, Aurora, CO, USA.
Colorado School of Public Health-Biostatistics and Informatics, CO, USA.
J Pediatr Hematol Oncol Nurs. 2022 May-Jun;39(3):155-167. doi: 10.1177/27527530211055988.
: Children with cancer experience distress and decreased quality of life (QOL). Creative arts therapy (CAT) is a therapeutic modality which may improve QOL. This study examined the relationship between CAT and QOL in children and adolescents with cancer. Secondary aims explored relationships between CAT and emotional reactions, resilience, and posture (to investigate future potential as an objective biomarker of QOL). : Children aged 3-18 years undergoing cancer treatments and a parent proxy completed the PedsQL3.0 Cancer Module, Faces Scale for emotional reactions, Resilience Scale in adolescents (>12 years), and an inclinometer to measure thoracic kyphosis before and after CAT. CAT exposure (number of sessions) was recorded. : Ninety-eight children with cancer (mean age 7.8 years, range 3-17) and parent proxy were enrolled. Of the 83 participants included in the final analysis, 18 received no CAT, 32 received low dose, and 33 received high dose CAT. A significant improvement in QOL was seen with high dose CAT in (slope change, = .015), but the overall time by group interaction was not significant. Slope change response patterns suggested that CAT led to improved posture as compared to no CAT (time by group interaction, = .044). : CAT may be an effective intervention to improve QOL in this population. Because initial evidence suggests that posture also improves with CAT, further investigation of posture as a potential objective biomarker of QOL is supported. Further study with a randomized controlled trial is warranted.
患癌儿童会经历痛苦且生活质量（QOL）下降。创造性艺术疗法（CAT）是一种可能改善生活质量的治疗方式。本研究调查了CAT与患癌儿童及青少年生活质量之间的关系。次要目标是探索CAT与情绪反应、恢复力和姿势之间的关系（以研究其作为生活质量客观生物标志物的未来潜力）。3至18岁正在接受癌症治疗的儿童及其家长代理人完成了儿童生活质量量表3.0癌症模块、情绪反应面部量表、青少年（>12岁）恢复力量表，以及在CAT前后测量胸椎后凸的倾角仪。记录CAT的治疗次数（疗程数）。招募了98名患癌儿童（平均年龄7.8岁，范围3至17岁）及其家长代理人。在纳入最终分析的83名参与者中，18人未接受CAT治疗，32人接受低剂量CAT治疗，33人接受高剂量CAT治疗。高剂量CAT治疗后生活质量有显著改善（斜率变化，=0.015），但总体组间时间交互作用不显著。斜率变化反应模式表明，与未接受CAT治疗相比，CAT治疗可改善姿势（组间时间交互作用，=0.044）。CAT可能是改善该人群生活质量的有效干预措施。由于初步证据表明姿势也会随着CAT治疗而改善，因此支持进一步将姿势作为生活质量潜在客观生物标志物进行研究。有必要进行进一步的随机对照试验研究。
