Nim Casper Glissmann, Kongsted Alice, Downie Aron, Vach Werner
Medical Research Unit, Spine Center of Southern Denmark, University Hospital of Southern, Odense, Denmark.
Department of Regional Health Research, University of Southern Denmark, Odense, Denmark.
Pain. 2022 Nov 1;163(11):e1104-e1114. doi: 10.1097/j.pain.0000000000002661. Epub 2022 Apr 25.
Low back pain (LBP) follows different pain trajectories, and patients seem to recognize their trajectory. This allows self-reported visual pain trajectories (SRVTs) to support patient-provider communication. Pain trajectories appear stable over time for many patients, but the evidence is sparse. Our objectives were to investigate the (1) temporal stability of SRVTs over 1 year concerning pain intensity and course patterns and (2) association of transitions between SRVTs and changes in pain and disability. This study used data from 2 prospective primary care cohorts: the Danish Chiropractic LBP Cohort (n = 1323) and the GLA:D Back cohort (n = 1135). Participants identified one of the 8 SRVTs at baseline and 12-month follow-up, each asking about LBP trajectories the preceding year. Trajectories were described using 2 subscales (intensity and pattern). Temporal stability was quantified by "stability odds ratios" (ORs), depicting the likelihood of staying in the same SRVT after 12 months compared with baseline, and by "preference ORs," depicting the likelihood of choosing a specific alternative SRVT at follow-up. Both ORs compare the observed proportion with the chance level. Finally, we examined associations between transitioning to a different trajectory and changes in clinical outcomes. Approximately 30% stayed in the same SRVT. The stability ORs were all >1. The preference ORs indicated that transitions occurred mainly to similar SRVTs differing in only 1 subscale. Transitions to less or more intense SRVTs were associated with changes in clinical outcomes in the expected direction. Despite distinctly different SRVTs identified, individuals reported relatively stable LBP phenotypes but with potential for change.
下背痛(LBP)呈现出不同的疼痛轨迹,且患者似乎能够识别自己的轨迹。这使得自我报告的视觉疼痛轨迹(SRVTs)有助于患者与医疗服务提供者之间的沟通。对于许多患者来说,疼痛轨迹随时间推移似乎是稳定的,但相关证据并不充分。我们的目标是研究:(1)SRVTs在1年时间里关于疼痛强度和病程模式的时间稳定性;(2)SRVTs之间的转变与疼痛及残疾变化之间的关联。本研究使用了来自2个前瞻性初级保健队列的数据:丹麦脊椎按摩疗法LBP队列(n = 1323)和GLA:D背部队列(n = 1135)。参与者在基线和12个月随访时识别出8种SRVTs中的一种,每种都询问了前一年的LBP轨迹。轨迹使用2个分量表(强度和模式)进行描述。时间稳定性通过“稳定性优势比”(ORs)进行量化,该指标描述了12个月后与基线相比保持在同一SRVT的可能性,以及通过“偏好优势比”进行量化,该指标描述了随访时选择特定替代SRVT的可能性。两个ORs都将观察到的比例与机会水平进行比较。最后,我们研究了转变为不同轨迹与临床结局变化之间的关联。大约30%的人保持在同一SRVT。稳定性ORs均>1。偏好优势比表明,转变主要发生在仅在1个分量表上不同的相似SRVT之间。向强度更低或更高的SRVT转变与临床结局在预期方向上的变化相关。尽管识别出了明显不同的SRVTs,但个体报告的LBP表型相对稳定,但仍有变化的可能性。