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日本：第二剂 SARS-CoV-2 疫苗接种后发生与纳武利尤单抗相关的 1 型糖尿病

Type 1 Diabetes Mellitus Associated with Nivolumab after Second SARS-CoV-2 Vaccination, Japan.

出版信息

Emerg Infect Dis. 2022 Jul;28(7):1518-1520. doi: 10.3201/eid2807.220127. Epub 2022 Apr 25.

DOI:10.3201/eid2807.220127
PMID:35468049
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9239866/
Abstract

Recently, along with increasing use of immune checkpoint inhibitors such as nivolumab, the incidence of immune-related adverse events, including type 1 diabetes mellitus, has become a serious problem. We report a patient who had immune checkpoint inhibitor‒associated type 1 diabetes mellitus that developed after a second mRNA-based SARS-CoV-2 vaccination.

摘要

最近，随着免疫检查点抑制剂（如纳武利尤单抗）的使用日益增多，包括 1 型糖尿病在内的免疫相关不良反应已成为一个严重的问题。我们报告了 1 例患者在接受第 2 剂基于 mRNA 的 SARS-CoV-2 疫苗接种后发生免疫检查点抑制剂相关 1 型糖尿病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a56/9239866/72c386f5f775/22-0127-F.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a56/9239866/72c386f5f775/22-0127-F.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a56/9239866/72c386f5f775/22-0127-F.jpg

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