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经内镜结扎夹(OTSC®)治疗消化性溃疡出血的疗效评价。

Over-the-scope-clip (OTSC®) as a rescue treatment for gastrointestinal bleeding secondary to peptic ulcer disease.

机构信息

Gastroenterología y Hepatología, Hospital Universitario Ramón y Cajal, España.

Gastroenterología y Hepatología, Hospital Universitario Ramón y Cajal.

出版信息

Rev Esp Enferm Dig. 2023 Feb;115(2):70-74. doi: 10.17235/reed.2022.8722/2022.

DOI:10.17235/reed.2022.8722/2022
PMID:35469413
Abstract

BACKGROUND AND AIMS

over-the-scope-clips (OTSC®) have been proposed as a rescue treatment for bleeding peptic ulcers. However, their effectiveness has not been evaluated in Spain.

METHODS

this retrospective and single-center study (January 2018-December 2021) assessed the technical success, clinical success and safety of the device within 30 days. All patients with upper gastrointestinal bleeding due to a peptic ulcer and treated with the OTSC® clip (OVESCO) as a rescue therapy were included in the study.

RESULTS

a total of eleven patients were included in the study, nine due to rebleeding and two due to persistent bleeding. Technical success was 81.9 % (9/11, confidence interval [CI] 95 %: 52-95 %). The per-protocol and intention-to-treat clinical success were 88.9 % (8/9, CI 95 %: 57-98 %) and 72.7 % (8/11, CI 95 %: 43-90 %), respectively. No device-related adverse effects were recorded.

CONCLUSION

the OTSC® clip was an effective and safe rescue therapy for bleeding peptic ulcers.

摘要

背景与目的

过内镜结扎夹(OTSC®)已被提议作为治疗消化性溃疡出血的抢救治疗方法。然而,其在西班牙的有效性尚未得到评估。

方法

本回顾性单中心研究(2018 年 1 月至 2021 年 12 月)评估了 30 天内该设备的技术成功率、临床成功率和安全性。所有因消化性溃疡出血且接受 OTSC®夹(OVESCO)作为抢救治疗的上消化道出血患者均纳入本研究。

结果

共纳入 11 例患者,9 例因再出血,2 例因持续出血。技术成功率为 81.9%(9/11,95%置信区间:52-95%)。按方案和意向治疗的临床成功率分别为 88.9%(8/9,95%置信区间:57-98%)和 72.7%(8/11,95%置信区间:43-90%)。未记录到与器械相关的不良事件。

结论

OTSC®夹是治疗消化性溃疡出血的一种有效且安全的抢救治疗方法。

相似文献

1
Over-the-scope-clip (OTSC®) as a rescue treatment for gastrointestinal bleeding secondary to peptic ulcer disease.经内镜结扎夹(OTSC®)治疗消化性溃疡出血的疗效评价。
Rev Esp Enferm Dig. 2023 Feb;115(2):70-74. doi: 10.17235/reed.2022.8722/2022.
2
Over-The-Scope Clip system as a first-line therapy for high-risk bleeding peptic ulcers: a retrospective study.内镜下套扎夹系统作为高危出血性消化性溃疡的一线治疗方法:一项回顾性研究。
Surg Endosc. 2021 May;35(5):2198-2205. doi: 10.1007/s00464-020-07625-1. Epub 2020 May 11.
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Over-the-Scope Clips Are More Effective Than Standard Endoscopic Therapy for Patients With Recurrent Bleeding of Peptic Ulcers.对于复发性消化性溃疡出血的患者,经内镜使用止血夹比标准内镜治疗更有效。
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One hundred and one over-the-scope-clip applications for severe gastrointestinal bleeding, leaks and fistulas.101例用于严重胃肠道出血、渗漏和瘘管的内镜夹应用。
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Use of over-the-scope clip (OTSC) versus standard therapy for the prevention of rebleeding in large peptic ulcers (size ≥1.5 cm): an open-labelled, multicentre international randomised controlled trial.经内镜结扎夹(OTSC)与标准治疗预防大于 1.5cm 消化性溃疡再出血的效果比较:一项开放标签、多中心国际随机对照试验
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Over-the-scope clip (OTSC) represents an effective endoscopic treatment for acute GI bleeding after failure of conventional techniques.经内镜结扎夹(OTSC)是一种有效的内镜治疗方法,适用于传统技术治疗失败后的急性胃肠道出血。
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