绿茶摄入与抑郁症状风险：TCLSIH 队列研究的结果。

Green tea consumption and risk of depressive symptoms: Results from the TCLSIH Cohort Study.

机构信息

Nutritional Epidemiology Institute and School of Public Health, Tianjin Medical University, Tianjin, China; Nutrition and Radiation Epidemiology Research Center, Institute of Radiation Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China.

Nutrition and Radiation Epidemiology Research Center, Institute of Radiation Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China.

出版信息

J Affect Disord. 2022 Aug 1;310:183-188. doi: 10.1016/j.jad.2022.04.112. Epub 2022 Apr 22.

DOI:10.1016/j.jad.2022.04.112

PMID:35469912

Abstract

BACKGROUND

The prospective studies on the effect of particular type of tea consumption, especially green tea, on depressive symptoms are limited.

OBJECTIVE

The aim of this study is to investigate the prospective association between green tea consumption and depressive symptoms in a large general adult population.

METHODS

This prospective cohort study investigated 7524 participants aged 25 to 90 years from May 2013 to December 2018 and they were free of cardiovascular disease, cancer, and depressive symptoms at baseline. Green tea consumption was obtained through a validated food frequency questionnaire. Depressive symptoms were assessed by using the Self-Rating Depressive Scale (SDS). The association between green tea consumption and depressive symptoms was analyzed by Cox proportional hazards regression models.

RESULTS

A total of 1064 first incident cases of depressive symptoms (SDS ≥45) occurred during 14,661 person-years of follow-up (median follow-up of 2.0 years). In the crude model, the hazard ratios (95% confidence intervals) were 1.00 (reference), 0.95 (0.81, 1.12), 0.97 (0.83, 1.14) and 0.95 (0.79, 1.14), respectively. After adjusting for demographic characteristics, lifestyle factors, and dietary intake, the multivariable adjusted hazard ratios (95% confidence intervals) were 1.00 (reference), 0.88 (0.74, 1.05), 0.84 (0.69, 1.02) and 0.78 (0.63, 0.97), respectively.

CONCLUSIONS

The prospective study suggests that frequent green tea consumption is associated with a decreased risk of depressive symptoms in the general Chinese population.

摘要

背景

关于特定类型的茶消费（尤其是绿茶）对抑郁症状影响的前瞻性研究有限。

目的

本研究旨在调查在大型普通成年人群中，绿茶消费与抑郁症状之间的前瞻性关联。

方法

这项前瞻性队列研究调查了 7524 名年龄在 25 至 90 岁之间的参与者，他们在基线时无心血管疾病、癌症和抑郁症状。绿茶的摄入量通过经过验证的食物频率问卷获得。使用自评抑郁量表（SDS）评估抑郁症状。采用 Cox 比例风险回归模型分析绿茶消费与抑郁症状之间的关系。

结果

在 14661 人年的随访期间（中位随访时间为 2.0 年），共发生了 1064 例首次出现抑郁症状（SDS≥45）的事件。在未经调整的模型中，风险比（95%置信区间）分别为 1.00（参考）、0.95（0.81，1.12）、0.97（0.83，1.14）和 0.95（0.79，1.14）。在调整了人口统计学特征、生活方式因素和饮食摄入后，多变量调整的风险比（95%置信区间）分别为 1.00（参考）、0.88（0.74，1.05）、0.84（0.69，1.02）和 0.78（0.63，0.97）。