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髋关节发育不良保髋治疗的研究进展:髋臼周围截骨术的系统评价和荟萃分析。

Hip survivorship following the Bernese periacetabular osteotomy for the treatment of acetabular dysplasia: A systematic review and meta-analysis.

机构信息

Department of Orthopaedic Surgery, University Orthopaedic, Hand and Reconstructive Microsurgery Cluster, National University Health System (NUHS), 1E Kent Ridge Road, NUHS Tower Block Level 11, Singapore 119074, Singapore.

Department of Orthopaedic Surgery, University Orthopaedic, Hand and Reconstructive Microsurgery Cluster, National University Health System (NUHS), 1E Kent Ridge Road, NUHS Tower Block Level 11, Singapore 119074, Singapore.

出版信息

Orthop Traumatol Surg Res. 2022 Jun;108(4):103283. doi: 10.1016/j.otsr.2022.103283. Epub 2022 Apr 22.

Abstract

INTRODUCTION

The Bernese periacetabular osteotomy (PAO) is a popular joint-preservation technique aimed at addressing the structural and biomechanical abnormalities associated with acetabular dysplasia. However, the prognostic factors and long-term survivorship of the native hip, with failure defined as conversion to total hip arthroplasty (THA), is poorly understood. Our study aims to address the following: (1) What is the estimated duration of survival of the native hip post-PAO, (2) What are some prognostic factors of functional outcome and (3) What is the complication rate and complications associated with PAO.

HYPOTHESIS

The Bernese PAO is able to result in favourable mid- to long-term outcomes conditional on a stringent patient selection criteria.

MATERIALS AND METHODS

A systematic review was performed using the PRISMA guidelines. All studies that reported on the outcomes of isolated Bernese PAO for the treatment of acetabular dysplasia were included.

RESULTS

A total of 24 studies (3471 patients, 3655 hips) were included at a mean follow-up duration of 54.2months (range: 1-336months). In total, 208 hips (6.03%; 95% CI: 5.25-6.94%) converted to THA at a mean duration of 4.71years (range: 1-240months). Univariate analysis identified advanced age beyond a follow-up duration of 6years (p=0.001) and preoperative Tönnis grade 2 and above (p<0.001) to be the most significant negative prognostic factors. Beyond a follow-up duration of 2years, intraoperative fluoroscopy proved to be a significant positive prognostic factor (p<0.001). Indications for PAO, obesity and gender were not found to be significant predictors of failure. Our study found the complication rate to be 23.5% (95% CI: 21.6-25.6%). The most common complications detailed are transient lateral femoral cutaneous nerve dysesthesia (8.24%; 95% CI: 7.02-9.65%), stress fracture (5.28%; 95% CI: 4.31-6.89%) and the delayed union, non-union or pseudoarthrosis of the ramus not necessitating surgical correction (3.73%, 95% CI: 2.93-4.75%).

DISCUSSION

PAO alters the natural history of the dysplastic hip with a 10- and 20-year survivorship of approximately 75.9% and 36.5% of patients respectively. The ideal patient should be below 40years old, with a preoperative Tönnis grade of 0 or 1. Intraoperative fluoroscopy is able to guide a better precision when re-orientating the acetabulum.

LEVEL OF EVIDENCE

IV; systematic review and meta-analysis.

摘要

介绍

伯尔尼髋臼周围截骨术(PAO)是一种流行的关节保留技术,旨在解决髋臼发育不良相关的结构和生物力学异常。然而,对于原发性髋关节,其预后因素和长期存活率(定义为转换为全髋关节置换术(THA))知之甚少。我们的研究旨在解决以下问题:(1)PAO 后原发性髋关节的预计生存时间是多少,(2)功能结果的预后因素有哪些,(3)PAO 相关的并发症发生率和并发症有哪些。

假设

伯尔尼 PAO 能够在严格的患者选择标准下获得良好的中期至长期结果。

材料和方法

采用 PRISMA 指南进行系统评价。所有报告伯尔尼 PAO 治疗髋臼发育不良的结果的研究均被纳入。

结果

共有 24 项研究(3471 名患者,3655 髋),平均随访时间为 54.2 个月(范围:1-336 个月)。共有 208 髋(6.03%;95%CI:5.25-6.94%)在平均 4.71 年(范围:1-240 个月)后转换为 THA。单因素分析发现,年龄超过 6 年(p=0.001)和术前 Tönnis 分级 2 级及以上(p<0.001)是最显著的负预后因素。超过 2 年的随访时间后,术中透视被证明是一个显著的正预后因素(p<0.001)。PAO 的适应证、肥胖和性别被发现不是失败的显著预测因素。我们的研究发现并发症发生率为 23.5%(95%CI:21.6-25.6%)。详细描述的最常见并发症是短暂性股外侧皮神经感觉异常(8.24%;95%CI:7.02-9.65%)、应力性骨折(5.28%;95%CI:4.31-6.89%)和股骨颈不愈合、延迟愈合或假关节,无需手术矫正(3.73%,95%CI:2.93-4.75%)。

讨论

PAO 改变了发育不良髋关节的自然史,10 年和 20 年的生存率分别约为 75.9%和 36.5%。理想的患者应在 40 岁以下,术前 Tönnis 分级为 0 或 1。术中透视能够更好地指导髋臼的重新定位。

证据水平

IV;系统评价和荟萃分析。

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