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构建用于预测伯尔尼髋臼周围截骨术后功能恢复的列线图。

Construction of a predictive nomogram for functional recovery after Bernese periacetabular osteotomy.

作者信息

Du Panzhihao, Gu Yange, Jin Wenshu, Li Shufeng, Yue Yaohui, Sun Huaqiang, Yan Xinfeng

机构信息

Shandong First Medical University & Shandong Academy Medical Sciences, Jinan, Shandong, China.

Department of Orthopedic Surgery, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Shandong Key Laboratory of Rheumatic Disease and Translational Medicine, Jinan, Shandong, China.

出版信息

Front Surg. 2024 Jul 26;11:1343823. doi: 10.3389/fsurg.2024.1343823. eCollection 2024.

Abstract

BACKGROUND AND PURPOSE

Surgical indications for Bernese periacetabular osteotomy (PAO) are well-established. However, the extent of postoperative functional recovery varies widely, as observed in clinical follow-ups. Thus, preoperative evaluation is crucial. This study aims to identify factors that influence functional recovery post-PAO and to develop a predictive nomogram.

PATIENTS AND METHODS

Retrospective data were collected between December 2016 and March 2022 at The First Affiliated Hospital of Shandong First Medical University. The dataset included demographic and imaging data of patients who underwent PAO. The least absolute shrinkage and selection operator (LASSO) regression was utilized to identify influencing factors, which were further analyzed using multivariate logistic regression to construct a predictive nomogram for post-PAO functional recovery.

RESULT

The analysis identified critical factors affecting functional recovery post-PAO, namely, the preoperative distance from the innermost surface of the femoral head to the ilioischial line, the surgical approach, preoperative acetabular depth, and the continuity of the preoperative Calve line. A nomogram was developed using these significant predictors. The model's validity was demonstrated by the receiver operating characteristic curve, with an area under the curve of 0.864. Additionally, the calibration curve confirmed the nomogram's accuracy, showing a strong correlation between observed and predicted probabilities, indicating high predictive accuracy.

CONCLUSION

This predictive nomogram effectively identifies patients most suitable for PAO, providing valuable guidance for selecting surgical candidates and determining the appropriate surgical approach.

摘要

背景与目的

伯尔尼髋臼周围截骨术(PAO)的手术适应症已得到充分确立。然而,临床随访发现,术后功能恢复程度差异很大。因此,术前评估至关重要。本研究旨在确定影响PAO术后功能恢复的因素,并开发一种预测列线图。

患者与方法

回顾性收集2016年12月至2022年3月在山东第一医科大学第一附属医院的数据。数据集包括接受PAO手术患者的人口统计学和影像学数据。采用最小绝对收缩和选择算子(LASSO)回归来确定影响因素,并进一步使用多变量逻辑回归进行分析,以构建PAO术后功能恢复的预测列线图。

结果

分析确定了影响PAO术后功能恢复的关键因素,即术前股骨头最内表面到髂坐线的距离、手术入路、术前髋臼深度以及术前卡尔维线的连续性。利用这些重要预测指标绘制了列线图。通过受试者工作特征曲线验证了模型的有效性,曲线下面积为0.864。此外,校准曲线证实了列线图的准确性,显示观察到的概率与预测概率之间有很强的相关性,表明预测准确性高。

结论

这种预测列线图有效地识别了最适合PAO的患者,为选择手术候选者和确定合适的手术入路提供了有价值的指导。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bcca/11310162/6383f97d14a2/fsurg-11-1343823-g001.jpg

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