Warszawski Uniwersytet Medyczny, Studenckie Koło Naukowe przy Klinice Psychiatrii Wieku Rozwojowego.
Warszawski Uniwersytet Medyczny, Klinika Psychiatrii Wieku Rozwojowego.
Psychiatr Pol. 2021 Dec 31;55(6):1421-1431. doi: 10.12740/PP/OnlineFirst/122350.
Autism spectrum disorder (ASD) is a heterogeneous group of neurodevelopmental disorders that can affect up to 2.6% of the population. Most of these people will have at least one other psychiatric disorder, often diagnosed with a delay or not recognized at all. This study describes the epidemiology, diagnostic difficulties and potential treatment of patients with ASD and comorbid bipolar disorder (BD). The prevalence of bipolar disorder in ASD is estimated at 5-8%. The study with the most numerous group included 700,000 children out of which 9,062 fulfilled ASD criteria at 16 - BD was found to be 6 times more prevalent in this group compared to the control group. Many factors affect the diagnosis. Patients with ASD often have limited insight into understanding the complex emotional states and difficulty in expressing them due to their impairment. The symptoms of bipolar disorder are in their case unspecific and differ from those occurring in the general population, which makes it difficult to make proper diagnosis. Despite the lack of research on the group of patients with ASD, psychometric tools designed to evaluate the general population are used to examine patients. This work aims to show the current state of knowledge and highlight areas that require further investigation.
自闭症谱系障碍（ASD）是一组异质性的神经发育障碍，影响人群可达 2.6%。这些人中大多数会有至少一种其他精神疾病，常被延迟诊断或根本未被识别。本研究描述了自闭症谱系障碍合并双相障碍（BD）患者的流行病学、诊断困难和潜在治疗方法。自闭症谱系障碍中双相障碍的患病率估计为 5-8%。研究中样本量最大的一组纳入了 70 万名儿童，其中 16 岁时有 9062 人符合自闭症谱系障碍标准，该组双相障碍的患病率是对照组的 6 倍。许多因素影响诊断。自闭症患者由于自身缺陷，往往对理解复杂的情绪状态和表达它们的能力有限，导致他们对自身状况缺乏洞察力。双相障碍的症状在他们身上不具有特异性，与一般人群中的症状不同，这使得做出正确诊断变得困难。尽管针对自闭症谱系障碍患者群体的研究较少，但仍使用设计用于评估普通人群的心理计量工具来检查患者。本研究旨在展示当前的知识状况，并强调需要进一步研究的领域。
