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散瞳剂会影响浆液性色素上皮脱离的升高吗?一例中心性浆液性脉络膜视网膜病变的病例报告。

Do mydriatics effect serous pigment epithelial detachment elevation? A case report on central serous chorioretinopathy.

作者信息

Mentes Jale, Oztas Zafer, Gobeka Hamidu Hamisi

机构信息

Department of Ophthalmology, Faculty of Medicine, Ege University, Izmir, Turkey.

Department of Ophthalmology, Medstar Antalya Hospital, Antalya, Turkey.

出版信息

Photodiagnosis Photodyn Ther. 2022 Sep;39:102877. doi: 10.1016/j.pdpdt.2022.102877. Epub 2022 Apr 23.

Abstract

This report aimed to determine if pupil-dilating eye drops (mydriatics) affected serous pigment epithelial detachment elevation in an eye with central serous chorioretinopathy using spectral domain-optical coherence tomography. A 47-year-old man presented to our clinic with metamorphopsia in his right eye, which had best corrected visual acuity of 20/20. Spectral domain-optical coherence tomography revealed minimal subretinal fluid and serous pigment epithelial detachment. During the follow-up examination after the final diagnosis of central serous chorioretinopathy and serous pigment epithelial detachment, different pigment epithelial detachment elevations on optical coherence tomography images before and after pupil dilation were found incidentally. These elevations were re-measured separately on different days before and after pupil dilation with 2.5% phenylephrine and 1% tropicamide to determine if this was a mydriatic-induced increase in pigment epithelial detachment elevation, which was eventually found to be the case. Mydriatics appeared to affect pigment epithelial detachment elevation in central serous chorioretinopathy. A thorough consideration of pre-dilation ocular examination and imaging data in central serous chorioretinopathy may be valuable.

摘要

本报告旨在利用光谱域光学相干断层扫描技术,确定散瞳眼药水(散瞳剂)是否会影响中心性浆液性脉络膜视网膜病变患者眼部的浆液性色素上皮脱离高度。一名47岁男性因右眼视物变形前来我院就诊,其最佳矫正视力为20/20。光谱域光学相干断层扫描显示视网膜下液极少且存在浆液性色素上皮脱离。在最终诊断为中心性浆液性脉络膜视网膜病变和浆液性色素上皮脱离后的随访检查中,偶然发现散瞳前后光学相干断层扫描图像上色素上皮脱离高度有所不同。分别在使用2.5%去氧肾上腺素和1%托吡卡胺散瞳前后的不同日期重新测量这些高度,以确定这是否是散瞳引起的色素上皮脱离高度增加,最终证实确实如此。散瞳剂似乎会影响中心性浆液性脉络膜视网膜病变患者的色素上皮脱离高度。对中心性浆液性脉络膜视网膜病变散瞳前的眼部检查和影像数据进行全面评估可能具有重要价值。

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