Department of Cardiology, Hisar Intercontinental Hospital, İstanbul, Turkey.
Department of Cardiology, Kartal Kosuyolu Training & Research Hospital, İstanbul, Turkey.
Biomark Med. 2022 Jun;16(8):613-622. doi: 10.2217/bmm-2021-1055. Epub 2022 Apr 27.
New parameters are emerging to predict prognosis in patients with ST-segment elevation myocardial infarction (STEMI). In this study we aimed to determine and compare the prognostic values of some metabolic indices in terms of predicting long-term mortality in patients with STEMI. A total of 1900 nondiabetic patients who presented with STEMI and underwent percutaneous coronary intervention were included in the study. Multivariable Cox proportional regression analysis was used to determine and compare the predictive performance of triglyceride-glucose (TyG) index, triglyceride-high-density lipoprotein ratio (Ty/HDL) and admission glucose. In multivariable Cox regression analysis, the model based on TyG index had better predictive performance than the Ty/HDL and admission blood glucose. The TyG index is more informative than Ty/HDL and admission glucose level to predict long-term all-cause mortality.
新的参数正在出现,以预测 ST 段抬高型心肌梗死(STEMI)患者的预后。本研究旨在确定和比较一些代谢指标在预测 STEMI 患者长期死亡率方面的预后价值。本研究共纳入 1900 例非糖尿病 STEMI 患者,并进行经皮冠状动脉介入治疗。多变量 Cox 比例风险回归分析用于确定和比较甘油三酯-葡萄糖(TyG)指数、甘油三酯-高密度脂蛋白比值(Ty/HDL)和入院时血糖的预测性能。在多变量 Cox 回归分析中,基于 TyG 指数的模型比 Ty/HDL 和入院时血糖具有更好的预测性能。TyG 指数比 Ty/HDL 和入院时血糖水平更能提供信息,以预测长期全因死亡率。