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两种不同艾哈迈德人工房水引流阀植入技术治疗难治性青光眼的长期手术效果:巩膜瓣法与巩膜隧道法对比

Long-term surgical outcomes of two different Ahmed Valve implantation techniques in refractory glaucoma: Scleral flap vs scleral tunnel.

作者信息

Papadopoulos Kosmas, Schröder Frank Michael, Sekundo Walter

机构信息

Department of Ophthalmology, Faculty of Medicine, 61061Philipps University of Marburg, Marburg, Germany.

出版信息

Eur J Ophthalmol. 2023 Jan;33(1):297-306. doi: 10.1177/11206721221097176. Epub 2022 Apr 27.

DOI:10.1177/11206721221097176
PMID:35473453
Abstract

PURPOSE

To compare the outcomes and complications of the partial-thickness scleral flap technique to the long scleral tunnel technique in patients who underwent mitomycin C (MMC)-augmented Ahmed glaucoma valve (AGV) implantation.

PATIENTS AND METHODS

In this retrospective study, we reviewed 139 eyes of 137 patients with refractory glaucoma who underwent AGV-Model FP7 implantation. The eyes were divided into the scleral flap group (n = 74) and the scleral tunnel group (n = 65).

RESULTS

The mean follow-up was 57.91 ± 18.18 months for the flap and 61.18 ± 15.13 months for the tunnel group (p = 0.2499). The postoperative intraocular pressure (IOP) at 1 to 6 years was significantly lower than the baseline IOP in each group (p < 0.001). The average number of postoperative glaucoma medications decreased in the tunnel group (p = 0.0001) and in the flap group (p = 0.6194) compared to baseline. No statistically significant differences in postoperative visual acuity (p = 0.6396) and cumulative success (p = 0.054) were noted between the two groups. Conjunctival erosion or tube migration only occurred in the flap group. Significantly more reoperations were performed in the flap than in the tunnel group (p = 0.048).

CONCLUSIONS

Both MMC-augmented AGV tube implantation methods lowered IOP. The flap technique was associated with higher rates of postoperative serious complications and more reoperations than the tunnel technique. Previous glaucoma surgery and the technique used to implant the surgical tube proved to be significant risk factors for conjunctival erosion.

摘要

目的

比较在接受丝裂霉素C(MMC)辅助的艾哈迈德青光眼引流阀(AGV)植入术的患者中,部分厚度巩膜瓣技术与长巩膜隧道技术的手术效果及并发症。

患者与方法

在这项回顾性研究中,我们回顾了137例难治性青光眼患者的139只接受AGV-FP7型植入术的眼睛。这些眼睛被分为巩膜瓣组(n = 74)和巩膜隧道组(n = 65)。

结果

巩膜瓣组的平均随访时间为57.91±18.18个月,巩膜隧道组为61.18±15.13个月(p = 0.2499)。每组术后1至6年的眼压均显著低于基线眼压(p < 0.001)。与基线相比,巩膜隧道组(p = 0.0001)和巩膜瓣组(p = 0.6194)术后青光眼药物的平均使用数量均减少。两组之间术后视力(p = 0.6396)和累积成功率(p = 0.054)无统计学显著差异。结膜糜烂或引流管移位仅发生在巩膜瓣组。巩膜瓣组的再次手术率显著高于巩膜隧道组(p = 0.048)。

结论

两种MMC辅助的AGV引流管植入方法均能降低眼压。与巩膜隧道技术相比,巩膜瓣技术术后严重并发症发生率更高,再次手术更多。既往青光眼手术及手术引流管植入技术被证明是结膜糜烂的重要危险因素。

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