超声睫状体成形术治疗难治性青光眼的疗效
Efficacy of ultrasound cyclo-plasty in patients with refractory glaucoma.
作者信息
Zhong Hui-Min, Liu Xiao-Hong, Huang Shou-Yue, Yao Hui-Ping, Zhong Yi-Sheng, Wang Jing
机构信息
Department of Ophthalmology, Ruijin Hospital Affiliated Medical School, Shanghai Jiao Tong University, Shanghai 200025, China.
Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University, Shanghai 200080, China.
出版信息
Int J Ophthalmol. 2025 Mar 18;18(3):420-423. doi: 10.18240/ijo.2025.03.08. eCollection 2025.
AIM
To assess the efficacy and safety of ultrasound cyclo-plasty (UCP) in lowering intraocular pressure (IOP) among Chinese patients suffering from refractory glaucoma.
METHODS
In this 12-month retrospective study, 28 patients with refractory glaucoma (IOP≥25 mm Hg) were treated with 8-second UCP using either 8 or 10 probe sectors. The principal measure of efficacy was the decrease in IOP at the following intervals after UCP: 1d, 1, 3, 6, and 12mo, with each measurement compared to baseline.
RESULTS
Mean IOP (in mm Hg) was reduced from 46.8±8.9 to 24.5±3.2, 27.0±4.8, 29.1±4.6, 26.1±4.5, and 28.3±4.8 at 1d, 1, 3, 6, and 12mo postoperatively, respectively. Compared to baseline, IOP reductions at these time points were 45.0%, 39.9%, 35.3%, 41.4%, and 36.7%, respectively. Most patients experienced relief from ocular pain after surgery. No cases of choroidal detachment or hypotony was observed.
CONCLUSION
UCP is effective in reducing IOP among Chinese patients with refractory glaucoma and shows a favorable safety profile.
目的
评估超声睫状体成形术（UCP）降低中国难治性青光眼患者眼压（IOP）的有效性和安全性。
方法
在这项为期12个月的回顾性研究中，28例难治性青光眼患者（眼压≥25 mmHg）接受了使用8或10个探头扇区的8秒超声睫状体成形术治疗。疗效的主要衡量指标是超声睫状体成形术后以下时间间隔的眼压降低情况：术后1天、1个月、3个月、6个月和12个月，每次测量均与基线进行比较。
结果
术后1天、1个月、3个月、6个月和12个月时，平均眼压（mmHg）分别从46.8±8.9降至24.5±3.2、27.0±4.8、29.1±4.6、26.1±4.5和28.3±4.8。与基线相比，这些时间点的眼压降低分别为45.0%、39.9%、35.3%、41.4%和36.7%。大多数患者术后眼痛缓解。未观察到脉络膜脱离或低眼压病例。
结论
超声睫状体成形术在降低中国难治性青光眼患者眼压方面有效，且安全性良好。
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