Second Faculty of Medicine, Charles University Prague, V Úvalu 84, 15006, Prague 5, Czechia.
Faculty of Humanities, Charles University Prague, Prague, Czechia.
Sci Rep. 2022 Apr 26;12(1):6823. doi: 10.1038/s41598-022-10892-8.
There remains a lack of conclusive evidence as to the merit of season of birth as a predictor of mental illness across contexts. We studied 72,370 individuals (55% women; mean age 66) from the Survey on Health, Ageing and Retirement in Europe. Depressive symptoms were assessed with EURO-D scale and symptoms of anxiety with modified Beck Anxiety Inventory. Multilevel modeling was used to assess the association of season of birth as well as month of birth with symptoms of depression and anxiety, by sex and region. Adjusting for sex and age, month of birth explained only 0.01% to 0.07% of anxiety and depressive symptoms with non-significant improvement in the overall models; using season of birth instead of month of birth added 0.00% to 0.04% of explained variance. When stratified by sex and European region, age explained 0.23% to 5.19% of anxiety and depressive symptoms; the addition of month of birth or season of birth improved the models by negligible amount. Season of birth and month of birth are not reliable predictors of anxiety and depression across the life course.
关于出生季节作为精神疾病预测指标的优势，在不同背景下仍缺乏确凿的证据。我们研究了来自欧洲健康、衰老和退休调查的 72370 个人（55%为女性；平均年龄 66 岁）。使用 EURO-D 量表评估抑郁症状，使用改良贝克焦虑量表评估焦虑症状。使用多层次模型，按性别和地区评估出生季节以及出生月份与抑郁和焦虑症状的关系。在调整性别和年龄后，出生月份仅能解释焦虑和抑郁症状的 0.01%至 0.07%，且整体模型无显著改善；使用出生季节而不是出生月份可使解释方差增加 0.00%至 0.04%。按性别和欧洲地区分层后，年龄可解释焦虑和抑郁症状的 0.23%至 5.19%；出生月份或出生季节的加入对模型的改善微乎其微。出生季节和出生月份并不是整个生命周期中焦虑和抑郁的可靠预测指标。
