由[2.2]对环芳烷衍生的各种取代（硫代）脲、氨基脲、硫代氨基脲、噻唑烷酮和恶二唑的高效合成

Efficient Synthesis of Various Substituted (Thio)Ureas, Semicarbazides, Thiosemicarbazides, Thiazolidones, and Oxadiazole Derived from [2.2]Paracyclophane.

作者信息

Alshammari Mohammed B, Aly Ashraf A, Bräse Stefan, Nieger Martin, Abd El-Haleem Lamiaa E

机构信息

Chemistry Department, College of Sciences and Humanities, Prince Sattam bin Abdulaziz University, P.O. 10, Box 83, Al-Kharij 11942, Saudi Arabia.

Chemistry Department, Faculty of Science, Minia University, 61519 El-Minia, Egypt.

出版信息

ACS Omega. 2022 Apr 6;7(15):12879-12890. doi: 10.1021/acsomega.2c00141. eCollection 2022 Apr 19.

The strategies of the syntheses of various (thio)ureas, semicarbazides, thiosemicarbazides, thiazolidones, and oxadiazole derived from the [2.2]paracyclophane molecule are achieved starting with 4-(2.2]paracyclophanyl)isocyanate. The structures of the obtained products were elucidated by NMR, mass spectrometry, and infrared (IR) spectroscopy in addition to high-resolution mass spectrometry (HRMS). X-ray structure analysis was also used to prove the assigned structure.