Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.
Universidade Federal de São Paulo, São Paulo, SP, Brazil.
Einstein (Sao Paulo). 2022 Apr 20;20:eAO6651. doi: 10.31744/einstein_journal/2022AO6651. eCollection 2022.
To detect and treat cases of viral hepatitis B, C and D in patients seen at the Native American Outpatient Clinic of Universidade Federal de São Paulo.
This sample comprised 81 indigenous recruited between 2018 and 2020. Volunteers were aged 7 months to 70 years (mean age of 28±20 years), belonged to 26 ethnic groups spanning the Brazilian territory and answered a questionnaire, which was attached to their medical records. Peripheral blood samples (20mL) were collected, transported to the Clinical Laboratory of Hospital Israelita Albert Einstein, processed, and tested for markers of viral hepatitis B, C and D.
In this study, 39 (48.1%) individuals were anti-HBs (+) only, 13 (16.0%) individuals were anti-HBs (+) and anti-HBc (+), and 28 (34.6%) individuals were negative for all markers. No anti-HBc IgM+ samples were found. No cases of hepatitis C and D were found.
This analysis provided evidence of previous infection by the hepatitis B virus. These findings led to prescription of vaccination against hepatitis B to all participants who were negative for all viral hepatitis B markers, given records of prior hepatitis B vaccination were unreliable.
在圣保罗联邦大学的美国原住民门诊中检测和治疗乙型、丙型和丁型病毒性肝炎患者。
本样本包括 2018 年至 2020 年间招募的 81 名土著人。志愿者年龄在 7 个月至 70 岁之间（平均年龄为 28±20 岁），属于跨越巴西领土的 26 个族群，并回答了一份问卷，该问卷附在他们的病历中。采集外周血样（20mL），送至爱因斯坦以色列医院临床检验科进行处理，并检测乙型、丙型和丁型病毒性肝炎标志物。
在这项研究中，39 名（48.1%）个体仅抗-HBs（+），13 名（16.0%）个体抗-HBs（+）和抗-HBc（+），28 名（34.6%）个体所有标志物均为阴性。未发现抗-HBc IgM+样本。未发现丙型和丁型肝炎病例。
本分析提供了乙型肝炎病毒既往感染的证据。这些发现导致对所有所有乙型肝炎病毒标志物均为阴性的参与者进行乙型肝炎疫苗接种，因为既往乙型肝炎疫苗接种记录不可靠。
