Taguchi K
Can J Surg. 1978 Jul;21(4):313-5.
The prevalence of carcinoma of the pancreas is increasing in North America. Primary prevention of this disorder is not yet possible and secondary prevention is difficult because most investigative procedures are either highly invasive or not universally available. The authors tested the efficacy of a simple immunologic assay, the leukocyte adherence inhibition (LAI) assay, in the detection of carcinoma of the pancreas. They investigated 55 patients who were divided into six groups--normal (control) patients (16) and those with carcinoma of the pancreas (9 patients), pancreatitis (15), other intra-abdominal carcinomas (9), obstructive jaundice (4) and pancreatic pseudocysts (2). The LAI assay proved highly effective in selecting patients who, at surgery, were shown to have carcinoma of the pancreas, but was not as effective in the groups. This assay may therefore prove valuable in the early evaluation of patients with a suspected pancreatic malignant condition.
在北美，胰腺癌的发病率正在上升。目前尚无法对这种疾病进行一级预防，而二级预防也很困难，因为大多数检测程序要么具有高度侵入性，要么并非普遍可用。作者测试了一种简单的免疫测定法，即白细胞黏附抑制（LAI）测定法在胰腺癌检测中的功效。他们对55名患者进行了研究，这些患者被分为六组——正常（对照）患者（16名）以及患有胰腺癌的患者（9名）、胰腺炎患者（15名）、其他腹腔内癌症患者（9名）、梗阻性黄疸患者（4名）和胰腺假性囊肿患者（2名）。LAI测定法在筛选那些在手术中被证明患有胰腺癌的患者方面被证明非常有效，但在其他组中效果不佳。因此，这种测定法可能在疑似胰腺恶性疾病患者的早期评估中具有价值。
