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[肺癌中的抗血管生成：现状、进展与困惑]

[Anti-angiogenesis in Lung Cancer: Current Situation, Progress and Confusion].

作者信息

Jiang Zhou, Chen Jianhua

机构信息

Department of Thoracic Medicine, Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, 
Hunan Cancer Hospital, Changsha 410006, China.

出版信息

Zhongguo Fei Ai Za Zhi. 2022 Apr 20;25(4):278-286. doi: 10.3779/j.issn.1009-3419.2022.101.16.

DOI:10.3779/j.issn.1009-3419.2022.101.16
PMID:35477192
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9051307/
Abstract

Lung cancer is a highly vascular tumors, over the past ten years, anti-angiogenes is has been proved to be an effective and highly promising combinational treatment. The data of the combination of anti-angiogenesis with chemotherapy, targeted therapy, immunotherapy has been constantly updating. Advanced lung cancer patients, no matter different groups or different stages of the disease, are benefited from anti-angiogenes. In this paper, based on the clinical status and unsolved problems, combined with the latest clinical and translational research data, we reviewed the current anti-angiogenesis treatment of lung cancer.
.

摘要

肺癌是一种血管丰富的肿瘤，在过去十年中，抗血管生成疗法已被证明是一种有效且极具前景的联合治疗方法。抗血管生成与化疗、靶向治疗、免疫治疗联合应用的数据一直在不断更新。晚期肺癌患者，无论疾病的不同分组或不同阶段，都从抗血管生成治疗中获益。本文基于临床现状和未解决的问题，结合最新的临床和转化研究数据，对目前肺癌的抗血管生成治疗进行综述。