Matsumoto Koji, Yokota Hajime, Yoda Takafumi, Ebata Ryota, Mukai Hiroki, Masuda Yoshitada, Uno Takashi
Department of Radiology, Chiba University Hospital, 1-8-1, Inohana, Chuo-ku, Chiba, Japan.
Diagnostic Radiology and Radiation Oncology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Sci Rep. 2022 Apr 27;12(1):6835. doi: 10.1038/s41598-022-10951-0.
Magnetic resonance vessel wall imaging is desirable for evaluating Kawasaki disease (KD)-associated coronary arterial lesions. To evaluate the reproducibility of three-dimensional turbo spin-echo (3D-TSE) and two-dimensional dual inversion-recovery turbo spin-echo (2D-DIR-TSE) for coronary vessel wall imaging in KD. Ten patients were prospectively enrolled. Coronary vessel wall imaging with axial-slice orientation 3D-TSE and 2D-DIR-TSE were acquired for cross-sectional images in aneurysmal and normal regions. Lumen area (LA), wall area (WA), and normalized wall index (NWI) of cross-sectional images were measured in both regions. Reproducibility between 3D-TSE and 2D-DIR-TSE was evaluated via intraclass correlation coefficients (ICCs) and Bland-Altman plots. 48 points (aneurysmal, 27; normal, 21) were evaluated. There were high ICCs between 3D-TSE and 2D-DIR-TSE in LA (0.95) and WA (0.95). In aneurysmal regions, 95% limits of agreement were LA, WA, and NWI of - 29.9 to 30.4 mm, - 18.8 to 15.0 mm, and - 0.22 to 0.20, respectively. In normal regions, the 95% limits of agreement were LA, WA, and NWI of - 4.44 to 4.38 mm, - 3.51 to 4.30 mm, and - 0.14 to 0.16, respectively. No fixed and proportional biases between 3D-TSE and 2D-DIR-TSE images in aneurysmal and normal regions were noted. 3D-TSE was reproducible with conventional 2D-DIR-TSE for coronary vessel wall assessment on KD.
磁共振血管壁成像对于评估川崎病(KD)相关的冠状动脉病变很有必要。为了评估三维快速自旋回波(3D-TSE)和二维双反转恢复快速自旋回波(2D-DIR-TSE)在KD患者冠状动脉壁成像中的可重复性。前瞻性纳入了10例患者。采用轴向切片方向的3D-TSE和2D-DIR-TSE进行冠状动脉壁成像,以获取动脉瘤区域和正常区域的横断面图像。在两个区域测量横断面图像的管腔面积(LA)、管壁面积(WA)和标准化管壁指数(NWI)。通过组内相关系数(ICC)和Bland-Altman图评估3D-TSE和2D-DIR-TSE之间的可重复性。共评估了48个点(动脉瘤区域27个,正常区域21个)。3D-TSE和2D-DIR-TSE在LA(0.95)和WA(0.95)方面具有较高的ICC。在动脉瘤区域,95%一致性界限的LA、WA和NWI分别为-29.9至30.4 mm、-18.8至15.0 mm和-0.22至0.20。在正常区域,95%一致性界限的LA、WA和NWI分别为-4.44至4.38 mm、-3.51至4.30 mm和-0.14至0.16。在动脉瘤区域和正常区域的3D-TSE和2D-DIR-TSE图像之间未发现固定偏差和比例偏差。3D-TSE与传统的2D-DIR-TSE在KD患者冠状动脉壁评估中具有可重复性。