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三维快速自旋回波与二维双反转恢复快速自旋回波在川崎病冠状动脉壁成像中的可重复性

Reproducibility between three-dimensional turbo spin-echo and two-dimensional dual inversion recovery turbo spin-echo for coronary vessel wall imaging in Kawasaki disease.

作者信息

Matsumoto Koji, Yokota Hajime, Yoda Takafumi, Ebata Ryota, Mukai Hiroki, Masuda Yoshitada, Uno Takashi

机构信息

Department of Radiology, Chiba University Hospital, 1-8-1, Inohana, Chuo-ku, Chiba, Japan.

Diagnostic Radiology and Radiation Oncology, Graduate School of Medicine, Chiba University, Chiba, Japan.

出版信息

Sci Rep. 2022 Apr 27;12(1):6835. doi: 10.1038/s41598-022-10951-0.

Abstract

Magnetic resonance vessel wall imaging is desirable for evaluating Kawasaki disease (KD)-associated coronary arterial lesions. To evaluate the reproducibility of three-dimensional turbo spin-echo (3D-TSE) and two-dimensional dual inversion-recovery turbo spin-echo (2D-DIR-TSE) for coronary vessel wall imaging in KD. Ten patients were prospectively enrolled. Coronary vessel wall imaging with axial-slice orientation 3D-TSE and 2D-DIR-TSE were acquired for cross-sectional images in aneurysmal and normal regions. Lumen area (LA), wall area (WA), and normalized wall index (NWI) of cross-sectional images were measured in both regions. Reproducibility between 3D-TSE and 2D-DIR-TSE was evaluated via intraclass correlation coefficients (ICCs) and Bland-Altman plots. 48 points (aneurysmal, 27; normal, 21) were evaluated. There were high ICCs between 3D-TSE and 2D-DIR-TSE in LA (0.95) and WA (0.95). In aneurysmal regions, 95% limits of agreement were LA, WA, and NWI of - 29.9 to 30.4 mm, - 18.8 to 15.0 mm, and - 0.22 to 0.20, respectively. In normal regions, the 95% limits of agreement were LA, WA, and NWI of - 4.44 to 4.38 mm, - 3.51 to 4.30 mm, and - 0.14 to 0.16, respectively. No fixed and proportional biases between 3D-TSE and 2D-DIR-TSE images in aneurysmal and normal regions were noted. 3D-TSE was reproducible with conventional 2D-DIR-TSE for coronary vessel wall assessment on KD.

摘要

磁共振血管壁成像对于评估川崎病(KD)相关的冠状动脉病变很有必要。为了评估三维快速自旋回波(3D-TSE)和二维双反转恢复快速自旋回波(2D-DIR-TSE)在KD患者冠状动脉壁成像中的可重复性。前瞻性纳入了10例患者。采用轴向切片方向的3D-TSE和2D-DIR-TSE进行冠状动脉壁成像,以获取动脉瘤区域和正常区域的横断面图像。在两个区域测量横断面图像的管腔面积(LA)、管壁面积(WA)和标准化管壁指数(NWI)。通过组内相关系数(ICC)和Bland-Altman图评估3D-TSE和2D-DIR-TSE之间的可重复性。共评估了48个点(动脉瘤区域27个,正常区域21个)。3D-TSE和2D-DIR-TSE在LA(0.95)和WA(0.95)方面具有较高的ICC。在动脉瘤区域,95%一致性界限的LA、WA和NWI分别为-29.9至30.4 mm、-18.8至15.0 mm和-0.22至0.20。在正常区域,95%一致性界限的LA、WA和NWI分别为-4.44至4.38 mm、-3.51至4.30 mm和-0.14至0.16。在动脉瘤区域和正常区域的3D-TSE和2D-DIR-TSE图像之间未发现固定偏差和比例偏差。3D-TSE与传统的2D-DIR-TSE在KD患者冠状动脉壁评估中具有可重复性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c942/9046194/4bac45bba51f/41598_2022_10951_Fig1_HTML.jpg

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