Sarıcam Esma, Ince Yusufoglu Selen, Kucuk Meltem, Geneci Ferhat, Ocak Mert, Celik H Hamdi
Department of Endodontics, Faculty of Dentistry, Ankara Yildirim Beyazit University, AnkaraTurkey.
Department of Endodontics, Faculty of Dentistry, Near East University, MersinTurkey.
Eur Oral Res. 2022 Jan 1;56(1):49-54. doi: 10.26650/eor.2022200002.
The study aimed to compare four irrigation methods for triple antibiotic paste (TAP) removal using micro-computed tomography (micro-CT) analysis.
Forty bovine central incisor teeth were selected, and the root canals were prepared up to #6 Peeso reamer drills. Equal portions of metronidazole, ciprofloxacin, and minocycline were used for the TAP preparation. The TAP was prepared by mixing the powder with distilled water (with a powder to liquid ratio of 1 mg/1 mL). The TAP was introduced to the canals with a lentulo spiral; then, the access cavities were temporarily sealed. After 21 days of storage, the teeth were randomly divided into four equal groups according to irrigation techniques: open-ended, side-vented, double side-vented needle irrigations and EndoActivator irrigation device. The TAP was removed using 17% EDTA (20 mL) and distilled water (5 mL) for all of the groups. The volume of the intracanal medicament before and after the irrigation procedure was recorded by scanning the samples with micro-CT, and the TAP percentage was calculated. The percentages obtained from each group were compared using ANOVA. The significance level was set at p<0.05.
The results showed that there was no statistically significant difference among the TAP percentage volumes removed by the different irrigation techniques.
The irrigation techniques used in this study showed similar TAP removal efficiency, however, they could not completely remove the TAP from the root canal systems.
本研究旨在使用微型计算机断层扫描（micro-CT）分析比较四种去除三联抗生素糊剂（TAP）的冲洗方法。
选取40颗牛的中切牙，根管预备至#6 Peeso扩孔钻。甲硝唑、环丙沙星和米诺环素按等量用于制备TAP。TAP通过将粉末与蒸馏水混合制备（粉末与液体比例为1 mg/1 mL）。用螺旋输送器将TAP导入根管；然后，临时封闭髓腔。储存21天后，根据冲洗技术将牙齿随机分为四组，每组数量相等：开放式、侧孔式、双侧孔式针冲洗和EndoActivator冲洗装置。所有组均使用17%乙二胺四乙酸（EDTA，20 mL）和蒸馏水（5 mL）去除TAP。通过用micro-CT扫描样本记录冲洗前后根管内药物的体积，并计算TAP百分比。使用方差分析比较每组获得的百分比。显著性水平设定为p<0.05。
结果表明，不同冲洗技术去除的TAP百分比体积之间无统计学显著差异。
本研究中使用的冲洗技术显示出相似的TAP去除效率，然而，它们不能完全从根管系统中去除TAP。
