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呋喃妥因与三联抗生素糊剂对环氧树脂封闭剂推出粘结强度影响的比较评估:一项研究。

Comparative evaluation of the effect of nitrofurantoin and triple antibiotic paste on the push-out bond strength of epoxy resin sealer: An study.

作者信息

Nair Rashmi, Khandelwal Shruti, Gohil Chitra, Maurya Neetu, Parakh Shrikant, Nawale Akanksha

机构信息

Department of Conservative Dentistry and Endodontics, Chhattisgarh Dental College and Research Institute, Rajnandgaon, Chhattisgarh, India.

出版信息

J Conserv Dent Endod. 2025 Feb;28(2):187-192. doi: 10.4103/JCDE.JCDE_795_24. Epub 2025 Feb 3.

Abstract

CONTEXT

Following chemomechanical preparation, the application of intracanal medicaments is recommended to further decrease the microbial count. To combat endodontic infections, the application of antibiotics as intracanal medicaments has been an option for years in endodontics.

AIM

The aim of this study was to compare and evaluate the effect of antibiotic pastes on the push-out bond strength (POBS) of resin-based root canal sealer.

MATERIALS AND METHODS

Forty-eight extracted single-rooted teeth were used after decoronation to a standardized root length of 15 mm. Canals were enlarged up to size F3 using Protaper rotary instruments. Samples were randomly divided into three groups according to the intracanal medicament used. Group A: Nitrofurantoin (NIT) Paste, Group B: Triple antibiotic paste (TAP), and Group C: Control group (without intracanal dressing). After removal of the medicament (endoactivator), obturation was done with AH Plus sealer. Push-out bond strength was calculated using universal testing machine.

STATISTICAL ANALYSIS

Data were analyzed using one-way ANOVA followed by Tukey and Kruskal-Wallis test (with a significance level of < 0.05).

RESULTS

Compared to the control group, the POBS significantly increased after using intracanal medicaments with < 0.05 (The results showed that the mean bond strength of TAP was highest, closely followed by NIT and least with the control group).

CONCLUSION

Under the limitations of this study, it can be concluded that the use of TAP and NIT increases the POBS of the Epoxy Resin Sealer.

摘要

背景

在进行化学机械预备后,建议使用根管内药物以进一步降低微生物数量。为对抗牙髓感染,多年来在牙髓病学中,使用抗生素作为根管内药物一直是一种选择。

目的

本研究的目的是比较和评估抗生素糊剂对树脂基根管封闭剂推出粘结强度(POBS)的影响。

材料与方法

48颗拔除的单根牙在截冠后使用,将牙根标准化至15mm长度。使用Protaper旋转器械将根管扩大至F3号。根据所使用的根管内药物,样本被随机分为三组。A组:呋喃妥因(NIT)糊剂,B组:三联抗生素糊剂(TAP),C组:对照组(无根管内敷料)。去除药物(根管激活剂)后,用AH Plus封闭剂进行根管充填。使用万能试验机计算推出粘结强度。

统计分析

使用单因素方差分析,随后进行Tukey检验和Kruskal-Wallis检验(显著性水平<0.05)对数据进行分析。

结果

与对照组相比,使用根管内药物后POBS显著增加(<0.05)(结果显示,TAP的平均粘结强度最高,其次是NIT,对照组最低)。

结论

在本研究的局限性下,可以得出结论,使用TAP和NIT可增加环氧树脂封闭剂的POBS。

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