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从骨盆入射角和胸椎后凸角推导出恢复理论上最佳的腰椎前凸角,对降低成人脊柱畸形术后机械性并发症的风险具有益处。

Restoring Theoretically Optimal Lumbar Lordosis Deduced from Pelvic Incidence and Thoracic Kyphosis has Advantages to Decrease the Risk of Postoperative Mechanical Complications in Adult Spinal Deformity.

作者信息

Wang Jingyu, Zhang Qianshi, Liu Fubing, Yuan Hui, Zhang Yi, Wang Xiaobin, Li Jing

机构信息

Department of Spine Surgery, Spinal Deformity Center, The Second Xiangya Hospital of Central South University, Changsha, China.

出版信息

Front Surg. 2022 Apr 11;9:860564. doi: 10.3389/fsurg.2022.860564. eCollection 2022.

Abstract

OBJECTIVE

To establish a regression formula for LL based on individual PI and TK in asymptomatic population aged over 50 years and evaluate its predictive power for the occurrence of postoperative mechanical complications in patients with adult spinal deformity (ASD).

METHODS

A total of 178 asymptomatic adults were recruited for the study. The association between LL and PI, LL and TK, was investigated to establish a predictive formula for ideal LL based on PI and TK. Additionally, 93 ASD patients undergoing posterior correction surgery were retrospectively analyzed. The absolute value of the gap between postoperative actual LL and theoretical LL was defined as ΔLL. Patients were classified into two groups depending on the presence or absence of mechanical complications. The demographic and radiological data of patients were compared between the two groups.

RESULTS

A significant association was found between LL and PI (= 0.599, 0.001), LL and TK (= 0.523, 0.001). A novel formula was developed as follows: LL = 0.7PI + 0.4TK + 1 ( = 0.524). In the validation cohort, 29 patients developed mechanical complications. Postoperative ΔLL (12.5 ± 7.6° vs. 7.0 ± 5.4°, = 0.001) significantly increased the incidence of mechanical complications. The most appropriate threshold of ΔLL for predicting mechanical complications was 9.8°. For patients whose ΔLL were 9.8° and >9.8°, the incidence of mechanical complications was 19.4% and 54.8%, respectively.

CONCLUSION

Ideal lumbar lordosis should be matched for PI and TK. The developed prediction formula for LL based on PI and TK in asymptomatic adults may help surgeons to understand the mechanisms of lumbar alignment generation and predict occurrence of mechanical complications after ASD surgery.

摘要

目的

建立基于50岁以上无症状人群个体骨盆入射角(PI)和胸椎后凸角(TK)的腰椎前凸(LL)回归公式,并评估其对成人脊柱畸形(ASD)患者术后机械性并发症发生的预测能力。

方法

共招募178例无症状成年人进行研究。研究LL与PI、LL与TK之间的关联,以建立基于PI和TK的理想LL预测公式。此外,对93例行后路矫正手术的ASD患者进行回顾性分析。术后实际LL与理论LL之间差距的绝对值定义为ΔLL。根据是否存在机械性并发症将患者分为两组。比较两组患者的人口统计学和放射学数据。

结果

发现LL与PI(=0.599,P=0.001)、LL与TK(=0.523,P=0.001)之间存在显著关联。开发了如下新公式:LL = 0.7×PI + 0.4×TK + 1(R² = 0.524)。在验证队列中,29例患者发生机械性并发症。术后ΔLL(12.5±7.6° vs. 7.0±5.4°,P=0.001)显著增加了机械性并发症的发生率。预测机械性并发症的ΔLL最合适阈值为9.8°。对于ΔLL为9.8°及>9.8°的患者,机械性并发症的发生率分别为19.4%和54.8%。

结论

理想的腰椎前凸应与PI和TK相匹配。基于无症状成年人PI和TK开发的LL预测公式可能有助于外科医生理解腰椎排列产生的机制,并预测ASD手术后机械性并发症的发生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a595/9035901/73fd2479f8a0/fsurg-09-860564-g001.jpg

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