基于三齿咪唑并[1,5 -]吡啶配体的双光子可激发硼配合物用于无重原子线粒体靶向光动力治疗

Two-photon excitable boron complex based on tridentate imidazo[1,5-]pyridine ligand for heavy-atom-free mitochondria-targeted photodynamic therapy.

作者信息

Hoshi Keita, Itaya Masami, Tahara Koki, Matsumoto Airi, Tabata Atsuhi, Nagamune Hideaki, Yoshida Yasushi, Hase Eiji, Minamikawa Takeo, Yasui Takeshi, Katayama Tetsuro, Furube Akihiro, Minagawa Keiji, Imada Yasushi, Yagishita Fumitoshi

机构信息

Department of Applied Chemistry, Tokushima University 2-1 Minamijosanjima Tokushima 770-8506 Japan

Department of Bioscience and Bioindustry, Tokushima University 2-1 Minamijosanjima Tokushima 770-8513 Japan.

出版信息

RSC Adv. 2021 Aug 2;11(42):26403-26407. doi: 10.1039/d1ra05059a. eCollection 2021 Jul 27.

We have synthesized a cyan fluorescent boron complex based on a tridentate imidazo[1,5-]pyridine ligand. The boron complex was found to have potential applications as not only a chiroptical material but also a heavy-atom-free mitochondria-targeted photosensitizer for cancer treatment.