Chen Yuxi, Meng Jiaqi, Cheng Kaiwen, Lu Qiang, Wei Ling, Lu Yi, Zhu Xiangjia
Department of Ophthalmology and Eye Institute, Eye and Ear, Nose, and Throat Hospital of Fudan University, Shanghai, China.
Key Laboratory of Myopia (Fudan University), National Health Commission, Shanghai, China.
Front Med (Lausanne). 2022 Apr 11;9:835475. doi: 10.3389/fmed.2022.835475. eCollection 2022.
This study aimed to investigate the influence of intraocular lens (IOL) weight on long-term IOL stability in highly myopic eyes.
A total of 205 highly myopic cataract eyes of 205 patients implanted with the MC X11 ASP (Group A, 86 eyes) or 920H IOL (Group B, 119 eyes) were included in this retrospective study. Eyes were divided into 3 subgroups according to the IOL power: low (≥-5 to <5 D), medium (≥5 to <14 D), and high (≥14 D) IOL power. At 3 years after surgery, IOL decentration and tilt, high-order aberrations, and anterior capsular opening (ACO) area were measured. The influence of IOL weight on long-term IOL stability was evaluated.
Group B had a significantly greater IOL weight than Group A (Group B vs. Group A: 28.31 ± 2.01 mg vs. 25.71 ± 4.62 mg, < 0.001). Correspondingly, Group B presented significantly greater overall and inferior decentration than Group A, especially for low and medium IOL power (all < 0.05). In both groups, overall and vertical decentration was significantly correlated with IOL weight (all < 0.05). Group B showed a significantly greater ACO area than Group A ( < 0.05). Multivariate analysis showed that decentration in Group A was affected by IOL weight, while decentration in Group B was affected by IOL weight and AL.
Higher IOL weight may lead to greater long-term IOL decentration in highly myopic eyes, while the haptic design may play a role in anterior capsular contraction.
本研究旨在探讨人工晶状体(IOL)重量对高度近视眼人工晶状体长期稳定性的影响。
本回顾性研究纳入了205例患者的205只高度近视白内障眼,这些眼睛植入了MC X11 ASP(A组,86只眼)或920H人工晶状体(B组,119只眼)。根据人工晶状体屈光度将眼睛分为3个亚组:低屈光度(≥-5至<5 D)、中屈光度(≥5至<14 D)和高屈光度(≥14 D)。术后3年,测量人工晶状体的偏心和倾斜、高阶像差以及前囊开口(ACO)面积。评估人工晶状体重量对人工晶状体长期稳定性的影响。
B组人工晶状体重量显著高于A组(B组 vs. A组:28.31±2.01 mg vs. 25.71±4.62 mg,<0.001)。相应地,B组的总体偏心和下方偏心显著大于A组,尤其是低、中屈光度的人工晶状体(均<0.05)。在两组中,总体偏心和垂直偏心均与人工晶状体重量显著相关(均<0.05)。B组的ACO面积显著大于A组(<0.05)。多因素分析显示,A组的偏心受人工晶状体重量影响,而B组的偏心受人工晶状体重量和眼轴长度影响。
较高的人工晶状体重量可能导致高度近视眼人工晶状体长期偏心更大,而襻的设计可能在前囊收缩中起作用。