血清白蛋白水平低与腹膜透析治疗患者的不良预后相关。
Low Serum Albumin Is Associated with Poor Prognosis in Patients Receiving Peritoneal Dialysis Treatment.
机构信息
Department of Nephrology, Beijing Lu-He Hospital, Capital Medical University, Beijing 101100, China.
出版信息
J Healthc Eng. 2022 Apr 18;2022:7660806. doi: 10.1155/2022/7660806. eCollection 2022.
BACKGROUND
The number of patients receiving dialysis treatment is sustainably increasing, especially peritoneal dialysis.
OBJECTIVES
It is necessary to find out potential factors that may indicate the prognosis of patients receiving peritoneal dialysis treatment.
METHODS
This study retrospectively involved 325 patients who received peritoneal dialysis treatment.
RESULTS
Low serum albumin (HR = 2.254; 95% CI: 1.534-3.311; < 0.001) and high FBG (Fasting blood glucose) (HR = 1.474; 95% CI: 1.025-2.120; =0.037) were risk factors for death in patients receiving peritoneal dialysis treatment. Serum albumin (AUC = 0.683; < 0.001) and creatinine (AUC = 0.625; < 0.001) exhibited value of prognosis prediction. Both high FBG (=0.005) and low albumin ( < 0.001) were associated with poor prognosis, and low albumin predicted poorer survival.
CONCLUSIONS
Low serum albumin and high fasting blood glucose were risk factors and associated with poor prognosis. Low albumin has a potential in predicting the prognosis of patients receiving peritoneal dialysis treatment.
背景
接受透析治疗的患者人数持续增加，尤其是腹膜透析。
目的
有必要找出可能预示腹膜透析治疗患者预后的潜在因素。
方法
本研究回顾性纳入 325 名接受腹膜透析治疗的患者。
结果
低血清白蛋白（HR=2.254；95%CI：1.534-3.311；<0.001）和高 FBG（空腹血糖）（HR=1.474；95%CI：1.025-2.120；=0.037）是腹膜透析治疗患者死亡的危险因素。血清白蛋白（AUC=0.683；<0.001）和肌酐（AUC=0.625；<0.001）对预后有预测价值。高 FBG（=0.005）和低白蛋白（<0.001）均与不良预后相关，低白蛋白预示着患者的生存更差。
结论
低血清白蛋白和高空腹血糖是危险因素，与不良预后相关。低白蛋白在预测腹膜透析治疗患者的预后方面具有潜力。
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