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β-酮酯酯交换反应的最新进展

Recent advances in the transesterification of β-keto esters.

作者信息

Hennessy M C, O'Sullivan T P

机构信息

School of Chemistry, University College Cork Cork Ireland

Analytical and Biological Chemistry Research Facility, University College Cork Cork Ireland.

出版信息

RSC Adv. 2021 Jul 2;11(37):22859-22920. doi: 10.1039/d1ra03513d. eCollection 2021 Jun 25.

DOI:10.1039/d1ra03513d
PMID:35480467
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9036406/
Abstract

The ability to selectively transesterify β-keto esters is a useful transformation in organic synthesis. The increasing interest in transesterification for the synthesis of compounds of pharmaceutical importance, as well as for biodiesel production, has led to the development of a variety of different approaches. This article aims to summarise recent advances in the transesterifications of β-keto esters. Particular interest has been paid to methodologies with minimal environmental impact.

摘要

选择性地对β-酮酯进行酯交换反应的能力在有机合成中是一种有用的转化方法。人们对酯交换反应在合成具有药物重要性的化合物以及生物柴油生产方面的兴趣日益浓厚，这导致了多种不同方法的发展。本文旨在总结β-酮酯酯交换反应的最新进展。特别关注了对环境影响最小的方法。

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